Effect of short term thyroxin withdrawal on health related quality of life in differentiated thyroid carcinoma patients

Basit Öğe Kaydı
dc.authorscopusid50461202500
dc.authorscopusid55987542100
dc.authorscopusid54880546000
dc.authorscopusid56725133200
dc.authorscopusid35949526800
dc.authorscopusid56490954700
dc.authorscopusid55800400300
dc.contributor.authorElboga, Umut
dc.contributor.authorElboga, Gülçin
dc.contributor.authorKalender, Ebuzer
dc.contributor.authorDemir, Hasan Deniz
dc.contributor.authorSahin, Ertan
dc.contributor.authorBasibuyuk, Mustafa
dc.contributor.authorAydogan, Fusun
dc.date.accessioned2024-09-19T15:47:05Z
dc.date.available2024-09-19T15:47:05Z
dc.date.issued2015
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractBackground: We aimed to study the HRQL in patients with differentiated thyroid carcinoma (DTC) during hypothyroidism due to thyroxin withdrawal, which is induced routinely for iodine-131 (I-131) whole body scan and ablative treatment. Methods: Between September 2011 and March 2012, eligible patients with DTC who were referred to our institution for diagnostic or therapeutic radioiodine administration under hypothyroid conditions due to thyroid hormone withdrawal were asked to complete the psychological instruments rating their HRQL and psychological status. HRQL was studied using the Short Form (SF-36), Hospital Anxiety and Depression Scale (HADS), Profile of Mood States (POMS), the total mood disturbance (TMD) score, Beck Depression Inventory (BDI).One hundred and forty three hypothyroid patients with DTC (F=101, M=42, age=58.7 yrs) who were also on low-iodine diet were included in this study. Hypothyroidism was induced by withdrawal of thyroxin replacement in all patients. Results: The results of SF-36 showed that the HRQL was significantly impaired in hypothyroid patients during withdrawal of thyroxin (physical component scale: 44.3 ± 9.5, mental component scale: 40.8 ± 10.2, p ? 0.001). Depression scores were in the normal or non-clinically relevant range: 4.1 ± 3.8 on the HADS-Depression and 8.3 ± 6.6 on the Beck Depression Index. However, the mean score of 28.8 ± 25.2 on the POMS TMD was within normal range. Conclusion: HRQL is impaired in hypothyroid patients with DTC during thyroxine withdrawal before I-131 whole body scan and radioiodine therapy. © 2015 Elboga U, et al.en_US
dc.identifier.doi10.4172/Psychiatry.1000254
dc.identifier.issn1994-8220
dc.identifier.issue2en_US
dc.identifier.scopus2-s2.0-84946780454en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.urihttps://doi.org/10.4172/Psychiatry.1000254
dc.identifier.urihttps://hdl.handle.net/20.500.12483/14968
dc.identifier.volume18en_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherIn House Publicationsen_US
dc.relation.ispartofAfrican Journal of Psychiatry (South Africa)en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectDTCen_US
dc.subjectHRQLen_US
dc.subjectThyroxine withdrawalen_US
dc.titleEffect of short term thyroxin withdrawal on health related quality of life in differentiated thyroid carcinoma patientsen_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

Scopus İndeksli Yayınlar Koleksiyonu