Evaluation of Four Adult Visceral Leishmaniasis Cases

Basit Öğe Kaydı
dc.authorscopusid56195646300
dc.authorscopusid6506955731
dc.authorscopusid57202031650
dc.authorscopusid54921238000
dc.authorscopusid16063919200
dc.authorscopusid6602284943
dc.contributor.authorÇabalak, Mehmet
dc.contributor.authorÇulha, Gülnaz
dc.contributor.authorKaya, Tuğba
dc.contributor.authorGürsoy, Didar
dc.contributor.authorİlhan, Gül
dc.contributor.authorÖzbilgin, Ahmet
dc.date.accessioned2024-09-19T15:47:02Z
dc.date.available2024-09-19T15:47:02Z
dc.date.issued2023
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractLeishmania infantum is the species responsible for visceral leishmaniasis [(VL), kala-azar], which is observed sporadically mainly in pediatric age groups in the Aegean, Mediterranean and Central Anatolian regions of Türkiye. The aim of this study is to evaluate the diagnosis, clinic, laboratory results and treatments of four adult patients with VL who applied to our hospital. The patients were referred to our hospital to investigate hematological malignancy. In the study, the data of four patients (three men, one woman; age range: 30-40 years) who were diagnosed with VL and treated in the infectious diseases clinic of our hospital between January 2022 and April 2022 were evaluated retrospectively. The diagnosis of VL was made according to appropriate clinical and physical examination findings, biochemical and serological tests (indirect fluorescent antibody test and rK39 rapid antigen test) and polymerase chain reaction (PCR) results, as well as the presence of amastigote forms of the parasite in bone marrow samples. Serology positivity was found in all patients, and bone marrow positivity was found in two patients. According to the results of RT-PCR in all patients, it was determined that the species causing the disease was L. infantum/L. donovani. Initially, the most common symptoms were fever, fatigue, and abdominal distension. None of the patients had an immunosuppressive condition. It was understood that all the patients lived in the rural area of Syria’s Idlib province. Hepatosplenomegaly, increased erythrocyte sedimentation rate, anemia, leukopenia and thrombocytopenia were found in all patients. The patients were treated with liposomal amphotericin-B (L-AMB). One patient did not come for follow-ups, the other three patients were found to have completely recovered in their follow-up. No recurrence was observed in any of the patients. In conclusion, VL should be considered in patients who apply to health institutions with complaints of fever, hepatosplenomegaly, increased erythrocyte sedimentation rate, anemia, leukopenia and thrombocytopenia. © Telif hakkı 2023 Türkiye Parazitoloji Derneği-Makale.en_US
dc.identifier.doi10.4274/tpd.galenos.2023.47550
dc.identifier.endpage279en_US
dc.identifier.issn1300-6320
dc.identifier.issue4en_US
dc.identifier.pmid38149450en_US
dc.identifier.scopus2-s2.0-85180823284en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage275en_US
dc.identifier.urihttps://doi.org/10.4274/tpd.galenos.2023.47550
dc.identifier.urihttps://hdl.handle.net/20.500.12483/14928
dc.identifier.volume47en_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isotren_US
dc.publisherGalenos Publishing Houseen_US
dc.relation.ispartofTurkiye Parazitoloji Dergisien_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectdiagnosisen_US
dc.subjecttreatmenten_US
dc.subjectVisceral leishmaniasisen_US
dc.titleEvaluation of Four Adult Visceral Leishmaniasis Casesen_US
dc.title.alternativeDört Erişkin Visseral Leishmaniasis Olgusunun Değerlendirilmesien_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

Scopus İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayınlar Koleksiyonu