Investigation of Trace Elements in Pterygium Tissue

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dc.contributor.authorNamuslu, Mehmet
dc.contributor.authorBalci, Mehmet
dc.contributor.authorCoskun, Mesut
dc.contributor.authorYagci, Ramazan
dc.contributor.authorCimen, Behzat
dc.contributor.authorCetin, Aysun
dc.contributor.authorAyyildiz, Abdullah
dc.date.accessioned2024-09-18T20:08:24Z
dc.date.available2024-09-18T20:08:24Z
dc.date.issued2013
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractPurpose: In this study, we compare the concentrations of the essential trace elements chromium (Cr), copper (Cu), selenium (Se), manganese (Mn), boron (B) and zinc (Zn) in both pterygium and normal conjunctiva and investigate the role they play in the development of pterygium. Methods: Included in the study were 38 patients with pterygium and 38 control patients in matching age groups who had been operated on for strabismus or cataracts and in whom conjunctiva samples were collected from the nasal limbus area. All conjunctiva samples were kept at -80 degrees C until the performance of the biochemical investigations. The B, Cr, Mn, Cu, Zn and Se levels in the samples were then measured. The levels of all tissue trace elements were determined by using Agilent 7500a Inductively Coupled Plasma-Mass Spectrometer (Agilent Technologies, Santa Clara, CA). Results: Cr, Mn, Zn and Se levels are significantly lower in the study group as compared to those of the control group (p<0.001 for all four values). Regarding the level of B, there was no significant difference between the groups. The Cu levels of almost all subjects in the control group and all subjects in the pterygium group were under the detection limit. Conclusions: These findings indicate that remarkable differences in Mn, Zn, Se and Cr levels exist in pterygium tissues. Further investigation of electrolyte composition of the conjunctiva is needed to understand the genesis and developmental mechanism of pterygium.en_US
dc.identifier.doi10.3109/02713683.2013.766755
dc.identifier.endpage530en_US
dc.identifier.issn0271-3683
dc.identifier.issue5en_US
dc.identifier.pmid23432702en_US
dc.identifier.scopus2-s2.0-84875883941en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage526en_US
dc.identifier.urihttps://doi.org/10.3109/02713683.2013.766755
dc.identifier.urihttps://hdl.handle.net/20.500.12483/8809
dc.identifier.volume38en_US
dc.identifier.wosWOS:000316952000002en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherInforma Healthcareen_US
dc.relation.ispartofCurrent Eye Researchen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectChromiumen_US
dc.subjectcopperen_US
dc.subjectmanganeseen_US
dc.subjectpterygiumen_US
dc.subjectseleniumen_US
dc.titleInvestigation of Trace Elements in Pterygium Tissueen_US
dc.typeArticleen_US

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