Effect of obesity on P-wave dispersion and QT dispersion in women

dc.contributor.authorSeyfeli, E.
dc.contributor.authorDuru, M.
dc.contributor.authorKuvandik, G.
dc.contributor.authorKaya, H.
dc.contributor.authorYalcin, F.
dc.date.accessioned2024-09-18T20:55:34Z
dc.date.available2024-09-18T20:55:34Z
dc.date.issued2006
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractObjective: The aim of this study was to investigate the effect of obesity on dispersion of P-wave duration and QTc interval in obese women. Methods: Forty-two obese women (Body mass index (BMI) 4073 kg/m(2), mean age 4579 years) and compared age-matched (BMI 2271 kg/m(2), mean age 41 +/- 6 years) twenty-five non-obese women were included in our study. Maximum and minimum P-wave duration, P-wave dispersion (difference between the maximum and the minimum P-wave duration), maximum and minimum QTc interval, and QTc dispersion (the difference between the maximum and the minimum QTc interval) were measured from 12-lead ECG. ECG's were transferred to a personal computer via a scanner and then used for magnification of 400 times by Adobe Photoshop software. Results: There was significant difference in BMI (40 +/- 3 vs 22 +/- 1 kg/m(2), P < 0.001, respectively) between obese and non-obese women. Obese women had higher Max. P-wave duration (116711 vs 94714 ms, P < 0.001), P-wave dispersion (51715 vs 26711 ms, P < 0.001), Max. QTc interval (449738 vs 419730 ms, P < 0.001) and QTc dispersion ( 57723 vs 38715 ms, P < 0.001) compared to non-obese women. A significant correlation was found between BMI and Max. P-wave duration (r = 0.584, P < 0.001), P-wave dispersion (r = 0.621, P < 0.001), Max. QTc interval (r = 0.410, P < 0.001), and QTc dispersion (r = 0.429, P < 0.001). In the linear regression analysis, compared to co-morbidity factors such as age, hypertension, diabetes mellitus and smoking, there was significant association between only BMI and electrocardiographic values (P-wave and QTc dispersion). Conclusion: We concluded that obesity caused significant increase in P-wave and QTc dispersion. Therefore, obese women may not only be under the risk of ventricular arrhythmias, but also they may under the risk of atrial arrhythmias.en_US
dc.identifier.doi10.1038/sj.ijo.0803233
dc.identifier.endpage961en_US
dc.identifier.issn0307-0565
dc.identifier.issn1476-5497
dc.identifier.issue6en_US
dc.identifier.pmid16432544en_US
dc.identifier.scopus2-s2.0-33744463875en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage957en_US
dc.identifier.urihttps://doi.org/10.1038/sj.ijo.0803233
dc.identifier.urihttps://hdl.handle.net/20.500.12483/11925
dc.identifier.volume30en_US
dc.identifier.wosWOS:000237862800012en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherNature Publishing Groupen_US
dc.relation.ispartofInternational Journal of Obesityen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectP-wave dispersionen_US
dc.subjectQTc dispersionen_US
dc.titleEffect of obesity on P-wave dispersion and QT dispersion in womenen_US
dc.typeArticleen_US

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