The effect of heart rate and pulse pressure on mean arterial pressure: the combined formula for calculation of mean arterial pressure

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dc.contributor.authorKaypakli, Onur
dc.contributor.authorOzgeyik, Mehmet
dc.date.accessioned2024-09-18T20:26:35Z
dc.date.available2024-09-18T20:26:35Z
dc.date.issued2021
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractBackground We demonstrate a new formula to predict mean arterial pressure (MAP) using corrections of the key factors associated with the inaccuracy of the standard formula: heart rate (HR) and pulse pressure (PP). Methods A total of 99 patients (50 men, 49 women; mean age 52.5 +/- 10.3 years), who underwent elective coronary angiography, were enrolled in our study. The arterial pressure was measured in the aortic root. MAP was measured digitally by the area-under-the-pressure-time curve method. We evaluated the accuracy of four different formulas: the standard formula, the formula of Razminia et al., the formula of Meaney et al. and the combined formula. Results PP coefficient deviation of the standard formula was negatively correlated with PP (R = -0,561, P < 0.001), and positively correlated with HR (R = 0,298, P = 0.003). Both R and R-2 values of the combined formula were higher than previous formulas. Accuracy parameters of the combined formula [root mean square error (RMSE): 1.801 mmHg, mean square residuals (MSR): 3.244 mmHg(2), Akaike information criterion (AIC): 401.4] were superior to the standard formula (RMSE: 1.902 mmHg, MSR: 3.620 mmHg(2), AIC: 412.3), the formula of Razminia et al. (RMSE: 2.022 mmHg, MSR: 4.089 mmHg(2), AIC: 424.3) and the formula of Meaney et al. (RMSE: 2.137 mmHg, MSR: 4.568 mmHg(2), AIC: 435.3). In the multivariate linear regression analysis, the combined formula was the only method that independently predicts the measured MAP (beta = 0,990, P < 0.001). Conclusion The combined formula is superior to previous formulas for accurately predicting MAP.en_US
dc.identifier.doi10.1097/MBP.0000000000000548
dc.identifier.endpage379en_US
dc.identifier.issn1359-5237
dc.identifier.issn1473-5725
dc.identifier.issue5en_US
dc.identifier.pmid34054029en_US
dc.identifier.scopus2-s2.0-85115021755en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage373en_US
dc.identifier.urihttps://doi.org/10.1097/MBP.0000000000000548
dc.identifier.urihttps://hdl.handle.net/20.500.12483/10417
dc.identifier.volume26en_US
dc.identifier.wosWOS:000693379500008en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherLippincott Williams & Wilkinsen_US
dc.relation.ispartofBlood Pressure Monitoringen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectheart rateen_US
dc.subjectmean arterial pressureen_US
dc.subjectpulse pressureen_US
dc.titleThe effect of heart rate and pulse pressure on mean arterial pressure: the combined formula for calculation of mean arterial pressureen_US
dc.typeArticleen_US

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