Evaluation of the hormones responsible for the gastrointestinal motility in cattle with displacement of the abomasum; ghrelin, motilin and gastrin

dc.authoridAytekin, Ismail/0000-0001-6794-5453
dc.contributor.authorOzturk, A. S.
dc.contributor.authorGuzel, M.
dc.contributor.authorAskar, T. K.
dc.contributor.authorAytekin, I.
dc.date.accessioned2024-09-18T21:06:26Z
dc.date.available2024-09-18T21:06:26Z
dc.date.issued2013
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractThis study provides the evidence of increased serum gastrointestinal motility hormone concentrations including ghrelin, motilin and gastrin in cattle with displacement of abomasum (DA). In this study, 38 cows with DA (21 left DA (LDA) and 17 right DA (RDA)) and 15 healthy controls were included. All cattle with DA were at the stage of postpartum one to eight weeks, and had clinical signs including anorexia, decreased milk yield and scanty, pasty faeces. Serum ghrelin, motilin and gastrin concentrations, and leptin concentration which is a functional antagonist of ghrelin, were determined by ELISA. Serum alanine aminotransferase (ALT), aspartate aminotransferase (AST), gamma-glutamyl transferase (GGT), Na, K, Cl, Ca and P concentrations were measured by spectrophotometer. In serum biochemical analysis, increases were seen on the serum ALT, AST and GGT activities; however, serum Na, K, Cl and P concentrations decreased in abomasal displacement compared with the control animals. The serum ghrelin, motilin and gastrin concentrations increased in the cattle with LDA and RDA, as compared with those in the healthy controls. On the other hand, serum leptin concentration decreased in the cattle with DA compared with the controls. Increases in the serum ghrelin, motilin and gastrin concentrations might be attributed to activation of gastrointestinal motility hormones to enhance of gastric emptying in impaired gastric motility and/or outlet occlusion in displaced abomasum.en_US
dc.description.sponsorshipScientific Research Projects Office of Mustafa Kemal University [PN: 1005M0110]en_US
dc.description.sponsorshipThis study was supported by the Scientific Research Projects Office of Mustafa Kemal University (PN: 1005M0110).en_US
dc.identifier.doi10.1136/vr.101322
dc.identifier.endpage+en_US
dc.identifier.issn0042-4900
dc.identifier.issn2042-7670
dc.identifier.issue24en_US
dc.identifier.pmid23723101en_US
dc.identifier.scopus2-s2.0-84879295815en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage636en_US
dc.identifier.urihttps://doi.org/10.1136/vr.101322
dc.identifier.urihttps://hdl.handle.net/20.500.12483/13588
dc.identifier.volume172en_US
dc.identifier.wosWOS:000321785500018en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherBmj Publishing Groupen_US
dc.relation.ispartofVeterinary Recorden_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectDairy-Cowsen_US
dc.subjectLeptinen_US
dc.subjectParametersen_US
dc.subjectStomachen_US
dc.titleEvaluation of the hormones responsible for the gastrointestinal motility in cattle with displacement of the abomasum; ghrelin, motilin and gastrinen_US
dc.typeArticleen_US

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