A subvulvar leiomyosarcoma in a Simmental cow-a case report
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Dosyalar
Tarih
2022
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Univ Zagreb Vet Faculty
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
In this case, a mass located subcutaneously in the perineal subvulvar region of a six-year-old Simmental cow was examined clinically, pathomorphologically and immunohistochemically. Macroscopically, the solitary, whitish yellow-tumor mass was 19x15x6 cm in size, weighed 1610 grams, and had a lobular structure with a few small cystic formations in the section. Histopathological examination revealed that the tumor parenchyma had smooth muscle-like cells with abundant cytoplasm, pleomorphic cells with blunt-ended or cigar-shaped nuclei, anisocytosis, anisokaryosis and karyomegaly. Immunohistochemically, strong positive expression for ??-SMA, vimentin, Ki67 and slight positive for desmin were found, while immulolabeling for pancytokeratin (AE1/AE3), S-100, CD31 and CD34 were negative. In conclusion, on the basis of these findings, the tumor was diagnosed as leiomyosarcoma.
Açıklama
Anahtar Kelimeler
surgery, histopathology, ?-SMA, vimentin, desmin, Ki67, perineal subvulvar leiomyosarcoma, Simmental cow
Kaynak
Veterinarski Arhiv
WoS Q Değeri
Q4
Scopus Q Değeri
Q4
Cilt
92
Sayı
2
