The role of combination pre- and postoperative albendazole therapy in the surgical management of liver hydatidosis

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dc.contributor.authorYetim, Brahim
dc.contributor.authorKilic, Erol
dc.date.accessioned2024-09-18T19:52:33Z
dc.date.available2024-09-18T19:52:33Z
dc.date.issued2018
dc.departmentHatay Mustafa Kemal Ãœniversitesien_US
dc.description.abstractAIMS: ALB is the most commonly used drug for the treatment of echinococcosis. The aim of the present study was to evaluate the effect of ALB using the intraoperative and perioperative periods as dual therapy. MATERIALS AND METHODS: Material of this retrospective study were the consecutive series of 98 patients operated for hepatic hydatidosis (HC) over a period of 7 years, at a single centre. Clinical examination, ultrasonography (US) and computed tomography (CT) were used for establishing diagnosis. Ninety-eight cases of hepatic hydatidosis were treated by albendazole intraoperatively and postoperatively together with surgery. Perioperative ALB treatment was given in a dose of 12-15 mg/ kg per day in four divided doses. The treatment started 2-28 days before the surgery when the diagnosis was established and continued for 2-24 months postoperatively in a cyclic monthly form. A total of 1.7 mg/mL ALB solution was used intraoperatively. Dual albendazole treatment (DALB) includes preoperative and postoperative oral ALB treatment and intraoperative irrigation of cystic cavity with ALB. RESULTS: In the follow-up period one patient died and there was one recurrence of hepatic hydatidosis.Morbidity rates were 10.89% . CONCLUSION: Results of this study suggest that ALB treatment with HC surgery is effective in the prevention of recurrences and/or secondary hydatidosis.en_US
dc.identifier.endpage533en_US
dc.identifier.issn0003-469X
dc.identifier.issn2239-253X
dc.identifier.issue6en_US
dc.identifier.startpage528en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12483/7509
dc.identifier.volume89en_US
dc.identifier.wosWOS:000455104700009en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.language.isoenen_US
dc.publisherEdizioni Luigi Pozzien_US
dc.relation.ispartofAnnali Italiani Di Chirurgiaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAlbendazoleen_US
dc.subjectRecurrens Liver hydatic cysten_US
dc.subjectSurgical treatmenten_US
dc.titleThe role of combination pre- and postoperative albendazole therapy in the surgical management of liver hydatidosisen_US
dc.typeArticleen_US

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