Graham-Little-Piccardi-Lassueur Syndrome: A Case Report

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dc.contributor.authorRifaioglu, Emine Nur
dc.contributor.authorSen, Tuba
dc.contributor.authorOzgur, Tumay
dc.contributor.authorSen, Bilge Bulbul
dc.contributor.authorEkiz, Ozlem
dc.date.accessioned2024-09-18T20:26:32Z
dc.date.available2024-09-18T20:26:32Z
dc.date.issued2015
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractA rare type of liken pilanopilaris, Graham-Little-Piccardi-Lassueur syndrome (GLPLS), is characterized by cicatricial alopecia of the scalp, follicular hyperkeratosis of trunk and extremities and non-cicatricial alopecia of axilla and pubis. A forty year-old woman admitted with hair loss and palpabl wheals on her body. On her dermatologic examination alopecic plaques with irregular border and atrophic appearance and milimetric papules around follicules on fronto-parietal part of scalp were detected. Also there were purple like-brown milimetric papules around follicules on both extensor part of distal arm, axilla, upper and lower back with alopecia on hairy areas. Additionally milimetric purplish papules on flexor area of wrists were accompanied to other signs. In histopathological investigation of the biopsy from scalp and back lesions were demonstrated orthokeratosis on superficial layer of epidermis, vacuolar degeneration and exocytosis on basal layer of epidermis and basal layer of follicular epithelium, perifollicular infiltration of mix type inflammatory cells, a few pigmentation deposited macrophages. The patient was diagnosed as GLPLS based on these symptoms and signs. Early diagnosis and treatment of this chronic, progressive characterized, rare type of lichen planopilaris is important. Treatments modalities could stop progression and provide partial remission, although they can't success complete improvement.en_US
dc.identifier.doi10.4274/tdd.1985
dc.identifier.endpage140en_US
dc.identifier.issn1307-7635
dc.identifier.issn1308-5255
dc.identifier.issue3en_US
dc.identifier.scopus2-s2.0-84942599952en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage138en_US
dc.identifier.urihttps://doi.org/10.4274/tdd.1985
dc.identifier.urihttps://hdl.handle.net/20.500.12483/10383
dc.identifier.volume9en_US
dc.identifier.wosWOS:000366969900006en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isotren_US
dc.publisherGalenos Yayinciliken_US
dc.relation.ispartofTurk Dermatoloji Dergisi-Turkish Journal of Dermatologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectHair lossen_US
dc.subjectGraham-Little-Piccardi-Lassueur syndromeen_US
dc.subjectlichen planopilarisen_US
dc.subjectpigmented lichenoid papulsen_US
dc.subjectscarring alopeciaen_US
dc.subjectpruritusen_US
dc.titleGraham-Little-Piccardi-Lassueur Syndrome: A Case Reporten_US
dc.typeArticleen_US

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