Increased Plasma Nesfatin-1 Levels in Patients with Obsessive Compulsive Disorder

Basit Öğe Kaydı
dc.contributor.authorBez, Yasin
dc.contributor.authorAri, Mustafa
dc.contributor.authorOzturk, Oktay Hasan
dc.contributor.authorOktar, Suleyman
dc.contributor.authorCan, Yesim
dc.date.accessioned2024-09-18T20:33:10Z
dc.date.available2024-09-18T20:33:10Z
dc.date.issued2012
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractIncreased plasma nesfatin-1 levels in patients with obsessive compulsive disorder Objective:To determine and compare the plasma nesfatin-1 (a satiety peptide) levels of patients with obsessive compulsive disorder (OCD) and healthy control subjects. Method: Plasma nesfatin-1 levels of 31 patients with OCD (18 females, 13 males) and 28 healthy control subjects (16 females and 12 males) similar to the study group in terms of weight, age, and gender were measured in this study. Severity of obsessions and compulsions both in OCD patients and control subjects were determined by using Yale-Brown Obsessive Compulsive Scale (Y-BOCS). ELISA method was used to measure plasma nesfatin-1 levels. Results: Median plasma nesfatin-1 levels in patients with OCD and healthy control subjects were 4.61 ng/ml (min-max: 1.28-8.11) and 2.0 ng/ml (min-max: 0.11-4.98) respectively. The observed difference in plasma nesfatin-1 levels between two groups was statistically significant (p<0.001). No statistically significant correlation was observed between Y-BOCS scores and plasma nesfatin-1 levels either in the study group (r=0.205, p=0.27) or in the control group (r=0.335, p=0.071). Conclusion: Increased plasma nesfatin-1 levels observed in patients with OCD suggest a potential role to nesfatin-1 in anxiety states besides its previosly known anorexigenic effects.en_US
dc.identifier.doi10.5455/bcp.20110627110925
dc.identifier.endpage9en_US
dc.identifier.issn1017-7833
dc.identifier.issue1en_US
dc.identifier.scopus2-s2.0-84857759176en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage5en_US
dc.identifier.urihttps://doi.org/10.5455/bcp.20110627110925
dc.identifier.urihttps://hdl.handle.net/20.500.12483/11334
dc.identifier.volume22en_US
dc.identifier.wosWOS:000303491300002en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherKure Iletisim Grubu A Sen_US
dc.relation.ispartofKlinik Psikofarmakoloji Bulteni-Bulletin of Clinical Psychopharmacologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectNesfatin-1en_US
dc.subjectobsessive compulsive disorderen_US
dc.subjectanxietyen_US
dc.subjectsatiety peptideen_US
dc.subjectappetiteen_US
dc.titleIncreased Plasma Nesfatin-1 Levels in Patients with Obsessive Compulsive Disorderen_US
dc.typeArticleen_US

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
Küçük Resim
İsim:
Tam Metin / Full Text
Boyut:
173.36 KB
Biçim:
Adobe Portable Document Format
İndir

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu