A Markov model developed for sodium channel currents in cerebellar Purkinje neurons

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dc.contributor.authorOzkaner, Vedat
dc.contributor.authorKayikcioglu, Temel
dc.date.accessioned2024-09-18T21:01:52Z
dc.date.available2024-09-18T21:01:52Z
dc.date.issued2006
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.descriptionIEEE 14th Signal Processing and Communications Applications -- APR 16-19, 2006 -- Antalya, TURKEYen_US
dc.description.abstractIn this study, a Markov model for gating kinetics of sodium channel currents in dissociated cerebellar Purkinje neurons is developed. The model is based on voltage-clamped, resurgent and action potential evoked currents, known as macroscopic currents. It is different from previously developed models. In this model, some-modifications are made in the number of states and channel rate constants. The model parameters are determined using trial and error procedure to minimizing the error between model responses and three experimental data sets. The developed sodium channel model reproduces quantitatively all features of the experimental data sets, with minor discrepancies.en_US
dc.description.sponsorshipIEEEen_US
dc.identifier.endpage+en_US
dc.identifier.isbn978-1-4244-0238-0
dc.identifier.scopus2-s2.0-34247170382en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage519en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12483/13052
dc.identifier.wosWOS:000245347800132en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isotren_US
dc.publisherIeeeen_US
dc.relation.ispartof2006 Ieee 14th Signal Processing and Communications Applications, Vols 1 and 2en_US
dc.relation.publicationcategoryKonferans Öğesi - Uluslararası - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectElectro-Physiological Propertiesen_US
dc.subjectIonic Currentsen_US
dc.subjectInactivationen_US
dc.subjectInvitroen_US
dc.subjectSlicesen_US
dc.subjectCellsen_US
dc.titleA Markov model developed for sodium channel currents in cerebellar Purkinje neuronsen_US
dc.typeConference Objecten_US

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