The Influence of Topical Cyclopentolate Instillation on Peripapillary and Macular Microvasculature Measured by Optical Coherence Tomography Angiography in Healthy Individuals

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dc.contributor.authorElbeyli, Ahmet
dc.contributor.authorKurtul, Bengi Ece
dc.date.accessioned2024-09-18T20:29:40Z
dc.date.available2024-09-18T20:29:40Z
dc.date.issued2021
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractPurpose: To investigate the influence of topical cyclopentolate 1%, as an anti-muscarinic mydriatic agent, on the peripapillary and macular microvasculature by optical coherence tomography angiography (OCT-A) in healthy adults. Methods: A total of 41 healthy adults without any systemic or ocular disease were enrolled for this prospective consecutive study. All patients underwent OCT-A measurements (OptoVue Inc., Freemont, CA, USA) to assess optic disc status for radial peripapillary capillary network (whole image, inside disc, and peripapillaiy capillary densities), and superficial and deep capillary plexus whole, foveal, parafoveal and perifoveal densities, and foveal avascular zone (FAZ) densities. Foveal retinal thicknesses and all quadrant retinal fiber layer thicknesses were also assessed. The 4.5 mm x 4.5 mm peripapillary and 6 mm x 6 mm macular OCT-A images were undertaken before and 30 min after instillation of topical cyclopentolate 1% to the right eyes. Results: The mean age of subjects was 38.14 +/- 14.10 years. All macular, optic disc, and FAZ densities, foveal retinal thicknesses, average, and all quadrant retinal fiber layer thicknesses were statistically similar between baseline and after administration of topical cyclopentolate 1% (P > 0.05). Conclusion: The current study demonstrated that pupillary dilation with topical cyclopentolate 1% seems to have no statistical effect on macular and peripepillary OCT-A measurements of healthy adults.en_US
dc.identifier.doi10.4103/joco.joco_84_21
dc.identifier.endpage443en_US
dc.identifier.issn2452-2325
dc.identifier.issue4en_US
dc.identifier.pmid35128191en_US
dc.identifier.scopus2-s2.0-85123213036en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage437en_US
dc.identifier.urihttps://doi.org/10.4103/joco.joco_84_21
dc.identifier.urihttps://hdl.handle.net/20.500.12483/11002
dc.identifier.volume33en_US
dc.identifier.wosWOS:000756904900011en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherWolters Kluwer Medknow Publicationsen_US
dc.relation.ispartofJournal of Current Ophthalmologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectMaculaen_US
dc.subjectOptic discen_US
dc.subjectOptical coherence tomography angiographyen_US
dc.subjectRetinaen_US
dc.subjectTopical cyclopentolateen_US
dc.titleThe Influence of Topical Cyclopentolate Instillation on Peripapillary and Macular Microvasculature Measured by Optical Coherence Tomography Angiography in Healthy Individualsen_US
dc.typeArticleen_US

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