Effects of acetylsalicylic acid on rats: An in vivo experimental study in azaserine-rat model
dc.authorid | YILDIZ, Hasan/0000-0001-5486-4005 | |
dc.contributor.author | Yildiz, Hasan | |
dc.contributor.author | Kalipci, Erkan | |
dc.contributor.author | Oztas, Haydar | |
dc.contributor.author | Yildiz, Deniz | |
dc.date.accessioned | 2024-09-18T19:48:02Z | |
dc.date.available | 2024-09-18T19:48:02Z | |
dc.date.issued | 2019 | |
dc.department | Hatay Mustafa Kemal Üniversitesi | en_US |
dc.description.abstract | Aim: The effect of acetylsalicylic acid (ASA) on thiol levels was studied in a rat model of azaserine carcinogenesis. Materials and Methods: ASA and azaserine were applied to the animals to research changes in cellular sulfhydryl (-SH) content and variations in free and protein-bound molecules containing the -SH group. Such effects in rats injected with azaserine were investigated at low (200 ppm) and high (400 ppm) concentrations of ASA over a relatively short (6 months) and a relatively long (12 months) period. Results: Changes in the hepatic, pancreatic, and renal -SH contents were also determined. Conclusion: Compared to the other tissues studied, the liver contained the highest levels of both free and protein-bound -SH. | en_US |
dc.identifier.doi | 10.4103/jcrt.JCRT_1319_16 | |
dc.identifier.endpage | 236 | en_US |
dc.identifier.issn | 0973-1482 | |
dc.identifier.issn | 1998-4138 | |
dc.identifier.issue | 1 | en_US |
dc.identifier.pmid | 30880783 | en_US |
dc.identifier.scopus | 2-s2.0-85063200907 | en_US |
dc.identifier.scopusquality | Q3 | en_US |
dc.identifier.startpage | 231 | en_US |
dc.identifier.uri | https://doi.org/10.4103/jcrt.JCRT_1319_16 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12483/7321 | |
dc.identifier.volume | 15 | en_US |
dc.identifier.wos | WOS:000461542500038 | en_US |
dc.identifier.wosquality | Q4 | en_US |
dc.indekslendigikaynak | Web of Science | en_US |
dc.indekslendigikaynak | Scopus | en_US |
dc.indekslendigikaynak | PubMed | en_US |
dc.language.iso | en | en_US |
dc.publisher | Wolters Kluwer Medknow Publications | en_US |
dc.relation.ispartof | Journal of Cancer Research and Therapeutics | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.subject | Acetylsalicylic acid | en_US |
dc.subject | azaserine | en_US |
dc.subject | rats | en_US |
dc.subject | sulfhydryl content | en_US |
dc.title | Effects of acetylsalicylic acid on rats: An in vivo experimental study in azaserine-rat model | en_US |
dc.type | Article | en_US |
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