Are the anticardiolipin antibodies a risk factor for coronary artery disease in chronic renal failure patients?

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dc.contributor.authorUcar, Edip
dc.contributor.authorKuvandik, Guven
dc.contributor.authorSert, Mehmet
dc.contributor.authorKuvandik, Ceren
dc.contributor.authorTemizkan, Aysegul
dc.contributor.authorBorazan, Ali
dc.date.accessioned2024-09-18T20:11:26Z
dc.date.available2024-09-18T20:11:26Z
dc.date.issued2008
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractObjective. It has been proposed that anticardiolipin (aCL) antibodies are a risk factor for coronary artery disease (CAD) in recently studies. In this study, we aimed to investigate the existence of coronary artery disease in dialysis patients who were aCL positive and undergoing hemodialysis and peritoneal dialysis due to end stage renal failure and also to determine its relationship with risk factors in patients with coronary artery disease. Methods. This study has been conducted in the end stage renal failure in 140 hemodialysis patients, 18 peritoneal dialysis patients, and 38 healthy controls. The urea, creatinine, total cholesterol, HDL cholesterol, LDL cholesterol, triglyceride, total protein, and albumin values are obtained. In all cases, aCL levels are investigated with ELISA method. Results. In the HD and CAPD patients, no significant relationship could be found between the age, gender, dialysis time, total cholesterol, HDL cholesterol, LDL cholesterol, total protein, and albumin values (p 0.05). HD and CAPD vs. controls (aCL), 9.2% (13/140), 11.1% (2/18) vs. 2.6% (1/38), p = 0.002. No significant difference was noted between aCL-positive and -negative patients in serum urea, creatinine, total cholesterol, HDL cholesterol, LDL cholesterol, triglyceride, total protein, and albumin levels. The coronary artery disease was determined in three patients out of 16 patients with aCL positivity. Conclusion. The prevalence of aCL antibodies positivity in our study was similar to the prevalence of aCL positivity in other studies. Therefore, we do not think aCL antibodies positivity is a risk factor for coronary artery disease.en_US
dc.identifier.doi10.1080/08860220802249017
dc.identifier.endpage795en_US
dc.identifier.issn0886-022X
dc.identifier.issn1525-6049
dc.identifier.issue8en_US
dc.identifier.pmid18791953en_US
dc.identifier.scopus2-s2.0-51849142752en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage791en_US
dc.identifier.urihttps://doi.org/10.1080/08860220802249017
dc.identifier.urihttps://hdl.handle.net/20.500.12483/8841
dc.identifier.volume30en_US
dc.identifier.wosWOS:000259197800005en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTaylor & Francis Ltden_US
dc.relation.ispartofRenal Failureen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectchronic renal diseaseen_US
dc.subjectcoronary artery diseaseen_US
dc.subjectanticardiolipin antibodiesen_US
dc.subjectechocardiographyen_US
dc.subjectcoronary angiographyen_US
dc.titleAre the anticardiolipin antibodies a risk factor for coronary artery disease in chronic renal failure patients?en_US
dc.typeArticleen_US

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