Novel Nanocomposite Hydrogels Based on Crosslinked Microbial Polysaccharide as Potential Bioactive Wound Dressings

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dc.authoridAlbu, Madalina Georgiana/0000-0001-9960-2244
dc.authoridGifu, Ioana Catalina/0000-0002-2854-1998
dc.authoridNISTOR, Cristina Lavinia/0000-0002-9200-5807
dc.authoridTrica, Bogdan/0000-0002-9948-6914
dc.authoridIanchis, Raluca/0000-0002-5540-2774
dc.authoridKaya, Durmus Alpaslan/0000-0003-3544-9214
dc.authoridMarin, Maria Minodora/0000-0001-8310-5075
dc.contributor.authorMarin, Maria Minodora
dc.contributor.authorKaya, Madalina Albu
dc.contributor.authorKaya, Durmus Alpaslan
dc.contributor.authorConstantinescu, Roxana
dc.contributor.authorTrica, Bogdan
dc.contributor.authorGifu, Ioana Catalina
dc.contributor.authorAlexandrescu, Elvira
dc.date.accessioned2024-09-18T20:26:54Z
dc.date.available2024-09-18T20:26:54Z
dc.date.issued2023
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractA multitude of dressings have been developed to promote wound repair, such as membranes, foams, hydrocolloids and hydrogels. In this study, a crosslinked polysaccharide hydrogel was mixed with a bioactive ingredient to synthesize a novel nanocomposite material to be used in wound healing. Variation of the ratio between hydrogel components was followed and its effect was analyzed in regard to swelling, degradation rate and thermo-mechanical behavior. The resulting crosslinked structures were characterized by FTIR and microscopy analyses. The antimicrobial activity of the crosslinked hydrogels loaded with bioactive agent was evaluated using two bacterial strains (Gram-positive Staphylococcus aureus and Gram-negative bacteria Escherichia Coli). All the results showed that the new synthesized biopolymer nanocomposites have adequate properties to be used as antibacterial wound dressings.en_US
dc.identifier.doi10.3390/ma16030982
dc.identifier.issn1996-1944
dc.identifier.issue3en_US
dc.identifier.pmid36769988en_US
dc.identifier.scopus2-s2.0-85147799046en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.urihttps://doi.org/10.3390/ma16030982
dc.identifier.urihttps://hdl.handle.net/20.500.12483/10586
dc.identifier.volume16en_US
dc.identifier.wosWOS:000930228300001en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherMdpien_US
dc.relation.ispartofMaterialsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjecthydrogelsen_US
dc.subjectantimicrobialen_US
dc.subjectpolysaccharideen_US
dc.subjectsalecanen_US
dc.subjectsilver nanoparticlesen_US
dc.titleNovel Nanocomposite Hydrogels Based on Crosslinked Microbial Polysaccharide as Potential Bioactive Wound Dressingsen_US
dc.typeArticleen_US

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