Enantioselective Addition of Diethylzinc to Aromatic Aldehydes Using Chiral Oxazoline-Based Ligands
Yükleniyor...
Tarih
2020
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Maik Nauka/Interperiodica/Springer
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Chiral oxazoline ligands containing an aromatic ring were prepared from norephedrine and pyrrole-2-carbonitrile or 2-hydroxybenzoyl chloride. The synthesized ligands were used in the copper-catalyzed asymmetric addition of diethylzinc to aromatic aldehydes to provide optically active 1-arylpropan-1-ols with high conversion (92%) and enantioselectivity (up to 99%ee).
Açıklama
Anahtar Kelimeler
asymmetric catalysis, enantioselective synthesis, chiral oxazoline-based ligands, 1, 2-addition
Kaynak
Russian Journal of Organic Chemistry
WoS Q DeÄŸeri
Q4
Scopus Q DeÄŸeri
Cilt
56
Sayı
7
