Insulin resistance in patients with post-adolescent acne

dc.authoridUstun, Ihsan/0000-0002-5848-1586
dc.contributor.authorBalta, Ilknur
dc.contributor.authorEkiz, Ozlem
dc.contributor.authorOzuguz, Pinar
dc.contributor.authorUstun, Ihsan
dc.contributor.authorKaraca, Semsettin
dc.contributor.authorKacar, Seval Dogruk
dc.contributor.authorEksioglu, Meral
dc.date.accessioned2024-09-18T21:05:14Z
dc.date.available2024-09-18T21:05:14Z
dc.date.issued2015
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractBackgroundPost-adolescent acne has been defined as acne in a patient aged >25years. Acne vulgaris first develops at the onset of puberty as a result of hormonal changes. During puberty, there is a transient decline in insulin sensitivity. We hypothesized that insulin resistance might persist after puberty in patients with post-adolescent acne. ObjectivesThis study was conducted in order to investigate the relationship between post-adolescent acne and insulin resistance. MethodsThe study population comprised 35 patients with post-adolescent acne and 35 healthy control subjects. The parameters measured were fasting blood glucose, insulin, aspartate aminotransferase (AST) and alanine aminotransferase (ALT), total cholesterol (TC), triglycerides, high-density lipoprotein cholesterol (HDL-C), and low-density lipoprotein cholesterol (LDL-C). The homeostasis model assessment of insulin resistance (HOMA-IR) index was calculated for each individual. ResultsNo significant differences were observed between patients with post-adolescent acne and control subjects in fasting blood glucose, fasting insulin, AST, ALT, triglyceride and HDL-C levels, and HOMA-IR index. There were also no correlations between these parameters and the severity of acne. ConclusionsThis study suggests that insulin resistance may not play a major role in the pathogenesis of post-adolescent acne. Hormonal changes, genetic susceptibility, stress, the use of cosmetics, drugs, and environmental factors should be considered in the development of post-adolescent acne.en_US
dc.identifier.doi10.1111/ijd.12426
dc.identifier.endpage666en_US
dc.identifier.issn0011-9059
dc.identifier.issn1365-4632
dc.identifier.issue6en_US
dc.identifier.pmid24961925en_US
dc.identifier.scopus2-s2.0-84929606811en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage662en_US
dc.identifier.urihttps://doi.org/10.1111/ijd.12426
dc.identifier.urihttps://hdl.handle.net/20.500.12483/13468
dc.identifier.volume54en_US
dc.identifier.wosWOS:000355135300027en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherWiley-Blackwellen_US
dc.relation.ispartofInternational Journal of Dermatologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectHomeostasis Model Assessmenten_US
dc.subjectGlycemic Indexen_US
dc.subjectClinical-Featuresen_US
dc.subjectVulgarisen_US
dc.subjectPrevalenceen_US
dc.subjectGlucoseen_US
dc.subjectAdultsen_US
dc.titleInsulin resistance in patients with post-adolescent acneen_US
dc.typeArticleen_US

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