Insulin resistance in patients with post-adolescent acne
dc.authorid | Ustun, Ihsan/0000-0002-5848-1586 | |
dc.contributor.author | Balta, Ilknur | |
dc.contributor.author | Ekiz, Ozlem | |
dc.contributor.author | Ozuguz, Pinar | |
dc.contributor.author | Ustun, Ihsan | |
dc.contributor.author | Karaca, Semsettin | |
dc.contributor.author | Kacar, Seval Dogruk | |
dc.contributor.author | Eksioglu, Meral | |
dc.date.accessioned | 2024-09-18T21:05:14Z | |
dc.date.available | 2024-09-18T21:05:14Z | |
dc.date.issued | 2015 | |
dc.department | Hatay Mustafa Kemal Üniversitesi | en_US |
dc.description.abstract | BackgroundPost-adolescent acne has been defined as acne in a patient aged >25years. Acne vulgaris first develops at the onset of puberty as a result of hormonal changes. During puberty, there is a transient decline in insulin sensitivity. We hypothesized that insulin resistance might persist after puberty in patients with post-adolescent acne. ObjectivesThis study was conducted in order to investigate the relationship between post-adolescent acne and insulin resistance. MethodsThe study population comprised 35 patients with post-adolescent acne and 35 healthy control subjects. The parameters measured were fasting blood glucose, insulin, aspartate aminotransferase (AST) and alanine aminotransferase (ALT), total cholesterol (TC), triglycerides, high-density lipoprotein cholesterol (HDL-C), and low-density lipoprotein cholesterol (LDL-C). The homeostasis model assessment of insulin resistance (HOMA-IR) index was calculated for each individual. ResultsNo significant differences were observed between patients with post-adolescent acne and control subjects in fasting blood glucose, fasting insulin, AST, ALT, triglyceride and HDL-C levels, and HOMA-IR index. There were also no correlations between these parameters and the severity of acne. ConclusionsThis study suggests that insulin resistance may not play a major role in the pathogenesis of post-adolescent acne. Hormonal changes, genetic susceptibility, stress, the use of cosmetics, drugs, and environmental factors should be considered in the development of post-adolescent acne. | en_US |
dc.identifier.doi | 10.1111/ijd.12426 | |
dc.identifier.endpage | 666 | en_US |
dc.identifier.issn | 0011-9059 | |
dc.identifier.issn | 1365-4632 | |
dc.identifier.issue | 6 | en_US |
dc.identifier.pmid | 24961925 | en_US |
dc.identifier.scopus | 2-s2.0-84929606811 | en_US |
dc.identifier.scopusquality | Q1 | en_US |
dc.identifier.startpage | 662 | en_US |
dc.identifier.uri | https://doi.org/10.1111/ijd.12426 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12483/13468 | |
dc.identifier.volume | 54 | en_US |
dc.identifier.wos | WOS:000355135300027 | en_US |
dc.identifier.wosquality | Q3 | en_US |
dc.indekslendigikaynak | Web of Science | en_US |
dc.indekslendigikaynak | Scopus | en_US |
dc.indekslendigikaynak | PubMed | en_US |
dc.language.iso | en | en_US |
dc.publisher | Wiley-Blackwell | en_US |
dc.relation.ispartof | International Journal of Dermatology | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.rights | info:eu-repo/semantics/closedAccess | en_US |
dc.subject | Homeostasis Model Assessment | en_US |
dc.subject | Glycemic Index | en_US |
dc.subject | Clinical-Features | en_US |
dc.subject | Vulgaris | en_US |
dc.subject | Prevalence | en_US |
dc.subject | Glucose | en_US |
dc.subject | Adults | en_US |
dc.title | Insulin resistance in patients with post-adolescent acne | en_US |
dc.type | Article | en_US |
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