Morphometry of the thoracolumbar vertebrae in sickle cell disease

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dc.contributor.authorSerarslan, Yurdal
dc.contributor.authorKalacı, Aydıner
dc.contributor.authorOzkan, Cenk
dc.contributor.authorDogramaci, Yunus
dc.contributor.authorCokluk, Cengiz
dc.contributor.authorYanat, Ahmet Nedim
dc.date.accessioned2024-09-18T20:32:57Z
dc.date.available2024-09-18T20:32:57Z
dc.date.issued2010
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractPatients with sickle cell disease (SCD) who have deformities and vertebral fractures due to osteoporosis may require surgery. Spinal surgeons must become familiar with the vertebral morphometry of patients with SCD and to that aim we have examined the morphometry of the thoracolumbar spine in these patients. A cohort of 100 patients with SCD was examined using plain thoraco lumbar anteroposterior/lateral radiographs and dual energy X-ray absorptiometry (DEXA). Vertebral morphometry (vertebral body diameters, pedicle, spinal canal and deformity) was assessed for different age groups. Results were compared to published studies of healthy subjects. The vertebral dimensions for the 16-20-year and the 21+-year-old groups were significantly smaller for females than males at most spinal levels, while measurements in the 6-10 years and 11-15 years age groups were similar across both sexes at most levels. No significant statistical difference was found between the diameters of the right and left pedicles. With the exception of the sagittal diameter, most of the dimensions of the vertebral bodies measured in SCD patients were less than those of healthy individuals; multiple deformities were also observed. Low bone density was noted in 32 patients. Our data highlight the differences in vertebral bone mineral density, anatomy and deformities in patients with SCD compared to healthy individuals. When considering surgical intervention for patients with SCD, it is important that pre-operative radiography and planning is undertaken, and that the surgeon is familiar with the geometry of the pedicles of the thoracolumbar vertebrae necessary for the safe insertion of pedicle screws. Osteoporosis must be considered when planning surgical interventions in these patients. (C) 2009 Elsevier Ltd. All rights reserved.en_US
dc.identifier.doi10.1016/j.jocn.2009.05.010
dc.identifier.endpage186en_US
dc.identifier.issn0967-5868
dc.identifier.issue2en_US
dc.identifier.pmid20006508en_US
dc.identifier.scopus2-s2.0-73449139386en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage182en_US
dc.identifier.urihttps://doi.org/10.1016/j.jocn.2009.05.010
dc.identifier.urihttps://hdl.handle.net/20.500.12483/11228
dc.identifier.volume17en_US
dc.identifier.wosWOS:000274445900007en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherElsevier Sci Ltden_US
dc.relation.ispartofJournal of Clinical Neuroscienceen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectMorphometryen_US
dc.subjectOsteoporosisen_US
dc.subjectPedicleen_US
dc.subjectPedicle screwen_US
dc.subjectSickle cell diseaseen_US
dc.subjectVertebraeen_US
dc.titleMorphometry of the thoracolumbar vertebrae in sickle cell diseaseen_US
dc.typeArticleen_US

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