Parameters predicting sperm retrieval rates during microscopic testicular sperm extraction in nonobstructive azoospermia

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dc.authoridKizilkan, Yalcin/0000-0002-4729-0100
dc.authoridTurunc, Tahsin/0000-0002-7936-2172
dc.authoridOzkardes, Hakan/0000-0002-7277-449X
dc.authoridtoksoz, serdar/0000-0002-2649-1157
dc.contributor.authorKizilkan, Yalcin
dc.contributor.authorToksoz, Serdar
dc.contributor.authorTurunc, Tahsin
dc.contributor.authorOzkardes, Hakan
dc.date.accessioned2024-09-18T20:32:51Z
dc.date.available2024-09-18T20:32:51Z
dc.date.issued2019
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractThe aim of this study was to investigate the predictive value of the parameters that might have an effect on the success of microscopic testicular sperm extraction (micro-TESE) in infertile patients with nonobstructive azoospermia (NOA). Between 2003 and 2014, 860 patients with NOA were retrospectively analysed. The effect of age, infertility duration, history of varicocelectomy, herniorrhaphy or orchiopexy, presence of solitary testis, tobacco use, previous testicular biopsy results, history of orchitis, usage of human chorionic gonadotropin in the past three months, presence of undescended or retractile testis, presence of varicocele, testicular volume, levels of serum follicle-stimulating hormone, luteinising hormone, and testosterone, presence of Klinefelter syndrome and micro-deletion of Y chromosome on sperm retrieval rates were evaluated. In 45.8% (n = 394) of the patients who underwent micro-TESE, spermatozoon was adequately obtained. Multiple logistic regression analysis demonstrated that previous successful testicular biopsy (OR = 15.346; GA = 5.45-43.16; p < .001) and higher testicular volumes significantly increase sperm retrieval rate in micro-TESE. The testicular volume cut-off as 11 ml was found to be the most significant factor. Although currently testicular biopsy result is not being used as a diagnostic method, it is significantly associated with micro-TESE result.en_US
dc.identifier.doi10.1111/and.13441
dc.identifier.issn0303-4569
dc.identifier.issn1439-0272
dc.identifier.issue11en_US
dc.identifier.pmid31583760en_US
dc.identifier.urihttps://doi.org/10.1111/and.13441
dc.identifier.urihttps://hdl.handle.net/20.500.12483/11169
dc.identifier.volume51en_US
dc.identifier.wosWOS:000496926700010en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.ispartofAndrologiaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectmicro-TESEen_US
dc.subjectnonobstructive azoospermiaen_US
dc.subjectsperm retrieval rateen_US
dc.subjecttesticular sperm extractionen_US
dc.titleParameters predicting sperm retrieval rates during microscopic testicular sperm extraction in nonobstructive azoospermiaen_US
dc.typeArticleen_US

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