Tonsilectomy in sickle cell diseases

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dc.authoridUgur, Mustafa/0000-0002-5922-2367
dc.contributor.authorHelvaci, Mehmet Rami
dc.contributor.authorGokce, Cumali
dc.contributor.authorDavran, Ramazan
dc.contributor.authorAcipayam, Can
dc.contributor.authorAkkucuk, Seckin
dc.contributor.authorUgur, Mustafa
dc.date.accessioned2024-09-18T20:57:02Z
dc.date.available2024-09-18T20:57:02Z
dc.date.issued2015
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractBackground: We tried to understand whether or not there are lowered prevalences of terminal consequences of sickle cell diseases (SCDs) with tonsilectomy. Methods: All cases with SCDs were taken into the study. Results: The study included 334 patients (164 females). There were 27 cases with tonsilectomy and 307 cases without. The mean ages, female ratios, and prevalences of associated thalassemia minors and smoking were similar in both groups (P>0.05 for all). Although the white blood cell and platelet counts of peripheric blood were higher in patients without tonsilectomy, the mean hematocrit value was lower in them, but the differences were nonsignificant probably due to the small sample size of the tonsilectomy group (P>0.05 for all). Similarly, although the painful crises per year, digital clubbing, leg ulcers, pulmonary hypertension, chronic obstructive pulmonary disease, rheumatic heart disease, avascular necrosis of bone, cirrhosis, stroke, and mortality were higher in cases without tonsilectomy, the differences were nonsignificant probably due to the same reason again (P>0.05 for all). Conclusion: There may be an inverse relationship between prevalence of tonsilectomy and severity of SCDs, and the tonsils may act as chronic inflammatory foci accelerating the chronic endothelial damage all over the body in such patients.en_US
dc.identifier.endpage4590en_US
dc.identifier.issn1940-5901
dc.identifier.issue3en_US
dc.identifier.pmid26064389en_US
dc.identifier.scopus2-s2.0-84929340442en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage4586en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12483/12255
dc.identifier.volume8en_US
dc.identifier.wosWOS:000355307300194en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherE-Century Publishing Corpen_US
dc.relation.ispartofInternational Journal of Clinical and Experimental Medicineen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectSickle cell diseasesen_US
dc.subjecttonsillectomyen_US
dc.subjectchronic endothelial damageen_US
dc.subjectatherosclerosisen_US
dc.titleTonsilectomy in sickle cell diseasesen_US
dc.typeArticleen_US

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