Malondialdehyde Level in the Cord Blood of Newborn Infants

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dc.authoridKaratekin, Guner/0000-0001-7112-0323
dc.authoridKaya, Aysem/0000-0003-3137-821X
dc.contributor.authorGulbayzar, Sayat
dc.contributor.authorArica, Vefik
dc.contributor.authorHatipoglu, Sami
dc.contributor.authorKaya, Aysem
dc.contributor.authorArica, Secil
dc.contributor.authorKaratekin, Guner
dc.date.accessioned2024-09-18T20:29:42Z
dc.date.available2024-09-18T20:29:42Z
dc.date.issued2011
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractObjective: In this study, we aim to demonstrate that measurement of the malondialdehyde (MDA) level in the umbilical cord blood of newborn infants born via cesarean section (C/S) and normal vaginal delivery (NVD) is indicative of oxidative stress during the perinatal period. Methods: The study was conducted at Bakirkoy Training and Research Hospital between January 2006 and April 2006 on 15 newborns born via elective C/S, 15 newborns born via emergency C/S, and 15 newborns born via normal vaginal delivery. Complete blood count, total bilirubin, glucose, creatinine phosphokinase (CPK), uric acid, iron, blood gas, and malondialdehyde levels were measured in the umbilical cord blood Findings: Malondialdehyde levels in the umbilical cord blood in the emergency C/S and NVD groups were found to be statistically and significantly higher than those in the elective C/S group. In the emergency C/S group, it was determined that the malondialdehyde level increased as the oxygen saturation of the umbilical cord blood increased. In the NVD group, a positive correlation was detected between the total bilirubin and malondialdehyde levels in the umbilical cord blood. In the emergency C/S group, the malondialdehyde level was recorded to be high in the infants with high level of uric acid in the umbilical cord blood. Conclusion: We concluded that the malondialdehyde level in umbilical cord blood could serve as an indication of perinatal oxidative stress and that it could thus help in preventing permanent damage.en_US
dc.identifier.endpage319en_US
dc.identifier.issn2008-2142
dc.identifier.issue3en_US
dc.identifier.pmid23056807en_US
dc.identifier.startpage313en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12483/11019
dc.identifier.volume21en_US
dc.identifier.wosWOS:000298623500008en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherIranian Scientific Society Medical Entomologyen_US
dc.relation.ispartofIranian Journal of Pediatricsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectMalondialdehydeen_US
dc.subjectOxidative Stressen_US
dc.subjectNewbornen_US
dc.subjectCord Blooden_US
dc.subjectCesarean Sectionen_US
dc.titleMalondialdehyde Level in the Cord Blood of Newborn Infantsen_US
dc.typeArticleen_US

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