Investigation of mean platelet volume in people with chronic hepatitis C virus infection

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dc.authorscopusid55185166900
dc.authorscopusid6603160510
dc.authorscopusid8927152600
dc.authorscopusid14038550900
dc.authorscopusid16041293500
dc.authorscopusid54793919100
dc.authorscopusid35489765100
dc.contributor.authorKöksaldi Motor, Vicdan
dc.contributor.authorEvirgen, Ömer
dc.contributor.authorÖnlen, Yusuf
dc.contributor.authorYula, Erkan
dc.contributor.authorBüyükkaya, Eyüp
dc.contributor.authorÇelik, M. Murat
dc.contributor.authorYengil, Erhan
dc.date.accessioned2024-09-19T15:43:40Z
dc.date.available2024-09-19T15:43:40Z
dc.date.issued2013
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractObjective: The mean platelet volume is a parameter routinely determined by complete blood count analyzer, and it is correlates with platelet function and activation. Platelet activation and aggregation play an important role in the pathophysiology of atherosclerosis. The mean platelet volume, which is a marker of platelet activation, is considered as a risk factor for atherothrombosis. Especially in recent years, many studies investigating the relationship between hepatitis C virus and atherosclerosis is noteworthy. The aim of the present study was to investigate mean platelet volume in people with chronic hepatitis C virus infection. Material and Methods: The patient group was constituted by 141 patients followed up due to chronic hepatitis C virus infection, while 107 healthy subjects acted as the control group. The data of patients with chronic hepatitis C virus infection and the control group were analyzed retrospectively. Results: The patients with chronic hepatitis C virus infection had a mean age of 53.5±12, 57 years, there were 57 (40.4%) males and 84 (59.6%) females. In the control group, there were 40 (37.4%) males and 67 (62.6%) females, and mean age was calculated as 53.2±12.8 years. While the platelet count was decreased in subjects with chronic hepatitis C virus infection, the mean platelet volume was increased. Conclusion: It was observed that mean platelet volume levels were not affected by the patient's genotype, RNA and alanine aminotransferase levels. The mean platelet volume was significantly higher in patients with chronic hepatitis C virus infection and this supported other investigations that established a connection between hepatitis C virus infection and the risk of atherothrombosis. © 2013 by Türkiye Klinikleri.en_US
dc.identifier.doi10.5336/medsci.2012-32123
dc.identifier.endpage1041en_US
dc.identifier.issn1300-0292
dc.identifier.issue4en_US
dc.identifier.scopus2-s2.0-84884692586en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage1037en_US
dc.identifier.urihttps://doi.org/10.5336/medsci.2012-32123
dc.identifier.urihttps://hdl.handle.net/20.500.12483/14495
dc.identifier.volume33en_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherTurkiye Kliniklerien_US
dc.relation.ispartofTurkiye Klinikleri Journal of Medical Sciencesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAtherosclerosisen_US
dc.subjectHepatitis Cen_US
dc.subjectPlatelet activationen_US
dc.titleInvestigation of mean platelet volume in people with chronic hepatitis C virus infectionen_US
dc.title.alternativeKronik hepatit C virüs enfeksiyonu olan kişilerde ortalama trombosit hacminin araşti{dotless}ri{dotless}lmasi{dotless}en_US
dc.typeArticleen_US

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