Positive correlation of CRP and fibrinogen levels as cardiovascular risk factors in early stage of continuous ambulatory peritoneal dialysis patients

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dc.authoridtekin, ishak ozel/0000-0002-9969-4254
dc.authoridDemircan, Nejat/0000-0002-0513-058X
dc.contributor.authorTekin, Ishak Ozel
dc.contributor.authorPocan, Bekir
dc.contributor.authorBorazan, Ali
dc.contributor.authorUcar, Edip
dc.contributor.authorKuvandik, Guven
dc.contributor.authorIlikhan, Sevil
dc.contributor.authorDemircan, Nejat
dc.date.accessioned2024-09-18T20:11:26Z
dc.date.available2024-09-18T20:11:26Z
dc.date.issued2008
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractWe aimed to study the relationship between the C-reactive protein (CRP), albumin, and fibrinogen as cardiovascular risk factors in continuous ambulatory peritoneal dialysis (CAPD) patients, in the early stage of their therapy. The study included 21 CAPD patients as the study group (SG) and age- and sex-matched 21 healthy patients as the control group (CG). History and physical exam data were obtained for all cases, and demographic baseline characteristics were taken. Twelve-hour fasting serum levels of glucose, total cholesterol, HDL cholesterol, LDL cholesterol, triglyceride, total protein, albumin, hemoglobin, CRP, and fibrinogen were obtained. There was no statistically significant difference between the SG and CG in baseline characteristics, including age, sex, body mass index (BMI), smoking, and family history of cardiovascular disease. However, diabetes mellitus (DM) and hypertension (HTN) were significantly more common among the study group. The average total protein, albumin, and hemoglobin levels were significantly lower, and the CRP and fibrinogen levels were significantly higher (p < 0.001) in the SG. A positive correlation was seen (r = 0.443, p < 0.05) among CRP and fibrinogen levels in SG. There was no correlation among the other parameters in SG. For CG, there was no correlation seen for any studied parameters. When patients with and without cardiovascular disease (CVD) were compared, no correlation was seen between CRP and other parameters. A positive correlation of CRP and fibrinogen levels as cardiovascular risk factors was shown in early stage of CAPD patients. The CAPD patients with elevated levels of CRP and fibrinogen should receive close follow-up for cardiovascular disease prevention.en_US
dc.identifier.doi10.1080/08860220701813350
dc.identifier.endpage225en_US
dc.identifier.issn0886-022X
dc.identifier.issn1525-6049
dc.identifier.issue2en_US
dc.identifier.pmid18300125en_US
dc.identifier.scopus2-s2.0-39749089861en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage219en_US
dc.identifier.urihttps://doi.org/10.1080/08860220701813350
dc.identifier.urihttps://hdl.handle.net/20.500.12483/8840
dc.identifier.volume30en_US
dc.identifier.wosWOS:000253580800016en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTaylor & Francis Ltden_US
dc.relation.ispartofRenal Failureen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectchronic renal diseaseen_US
dc.subjectcoronary artery diseaseen_US
dc.subjectanticardiolipin antibodiesen_US
dc.subjectechocardiographyen_US
dc.subjectcoronary angiographyen_US
dc.titlePositive correlation of CRP and fibrinogen levels as cardiovascular risk factors in early stage of continuous ambulatory peritoneal dialysis patientsen_US
dc.typeArticleen_US

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