ACTIVITY OF OLEIC ACID ON BIOFILM FORMATION OF S. aureus

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dc.authorscopusid58195365100
dc.authorscopusid35612683100
dc.contributor.authorYaprak, Elif
dc.contributor.authorDuran, Nizami
dc.date.accessioned2024-09-19T15:41:16Z
dc.date.available2024-09-19T15:41:16Z
dc.date.issued2022
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description9th International Conference on Advanced Materials and Systems, ICAMS 2022 -- 26 October 2022 through 28 October 2022 -- Bucharest -- 292469en_US
dc.description.abstractOleic acid is a naturally occurring fatty acid in animal and vegetable oils and has been shown to have a wide variety of pharmacological effects. It aimed to investigate the efficacy of oleic acid on the adhesion and invasion of S. aureus to the host cell and biofilm production. The standard S. aureus strain (ATCC 25923) was used in the experiments. Cytotoxicity tests of oleic acid were performed in the Vero cell line. Bacterial adhesion and invasion rates and activities on slime formation in cells treated with oleic acid were evaluated compared to the control group. Slime formation tests were evaluated phenotypically on Congo red agar. In the study, it was determined that oleic acid was effective in both cellular adhesion and invasion in terms of colony number in cell cultures treated with 0.156 ?g/ml concentration of oleic acid. In addition, it was determined that slime production was significantly inhibited in bacterial cultures treated with oleic acid. Oleic acid prevents cells from attaching to bacteria and has an inhibitory effect on the virulence of bacteria. This activity of oleic acid may be due to its modulatory effect on cellular processes, and its bacterial virulence may be related to its effect on bacterial metabolism. © 2022 Toate drepturile asupra acestei edi?ii sunt rezervate editorilor.en_US
dc.identifier.doi10.24264/icams-2022.III.21
dc.identifier.endpage386en_US
dc.identifier.issn2068-0783
dc.identifier.scopus2-s2.0-85153475522en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage381en_US
dc.identifier.urihttps://doi.org/10.24264/icams-2022.III.21
dc.identifier.urihttps://hdl.handle.net/20.500.12483/14147
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherInst. Nat. Cercetare-Dezvoltare Text. Pielarieen_US
dc.relation.ispartofICAMS Proceedings of the International Conference on Advanced Materials and Systemsen_US
dc.relation.publicationcategoryKonferans Öğesi - Uluslararası - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectadhesionen_US
dc.subjectbiofilmen_US
dc.subjectinvasionen_US
dc.subjectoleic aciden_US
dc.titleACTIVITY OF OLEIC ACID ON BIOFILM FORMATION OF S. aureusen_US
dc.typeConference Objecten_US

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