Ultrasonographic shear wave elastography of the thyroid in patients with sickle cell anemia

Basit Öğe Kaydı
dc.authoridILHAN, GUL/0000-0003-1616-6358
dc.authoridozcan, oguzhan/0000-0001-7486-503X
dc.authoridDIRICAN, EMRE/0000-0003-3550-1326
dc.contributor.authorBurakgazi, Gulen
dc.contributor.authorIlhan, Gul
dc.contributor.authorOzcan, Oguzhan
dc.contributor.authorDirican, Emre
dc.date.accessioned2024-09-18T19:54:20Z
dc.date.available2024-09-18T19:54:20Z
dc.date.issued2022
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractBackground Although thyroid radiology has been conducted in patients with sickle cell anemia (SCA), to our knowledge, there is no report of thyroid gland assessment using ultrasonographic shear wave elastography (US-SWE). Objectives To determine values for ultrasonographic US-SWE of the thyroid in patients with SCA and correlations between thyroid elasticity and biochemical variables used to evaluate thyroid function. Methods Prospective case-control observational study of 36 patients with SCA and 33 healthy volunteer controls. US-SWE measurements of thyroid gland parenchyma and biochemical parameters of the participants were obtained and compared, and the diagnostic accuracy of elasticity was determined. Results The thyroid volume was smaller in patients with SCA than that in controls (P = 0.001). Compared with the controls, the patients with SCA had significantly lower serum levels of free triiodothyronine (fT3) (P = 0.004) and thyroglobulin (Tg) (P = 0.001) and significantly higher levels of thyroid-stimulating hormone (P = 0.028). Thyroid stiffness was significantly higher in the left lobe (LL) of the patients with SCA than in the controls (P = 0.003). In the patients with SCA, we found a significant correlation between right lobe (RL) and LL stiffness and serum levels of Tg (RL [r = -0.439] and LL [r = -0.484]; P = 0.021) and fT3 (RL [r = -0.463] and LL [r = -0.386]; P = 0.012). Receiver operating characteristic (ROC) curve analysis of thyroid elasticity that represented a diagnosis of SCA found a cutoff of >7.31 kPa, a sensitivity of 52.0%, and a specificity of 72.0% for the RL (P = 0.316, area under the curve [AUC] 0.570), and a cutoff of >8.06 kPa, a sensitivity of 58.0%, and a specificity of 84.0% for the LL (P = 0.011, AUC 0.680). Conclusions US-SWE can be used to follow up thyroid changes in patients with SCA.en_US
dc.identifier.doi10.2478/abm-2022-0017
dc.identifier.endpage143en_US
dc.identifier.issn1905-7415
dc.identifier.issn1875-855X
dc.identifier.issue3en_US
dc.identifier.pmid37551381en_US
dc.identifier.scopus2-s2.0-85139040178en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage137en_US
dc.identifier.urihttps://doi.org/10.2478/abm-2022-0017
dc.identifier.urihttps://hdl.handle.net/20.500.12483/7669
dc.identifier.volume16en_US
dc.identifier.wosWOS:000847274500005en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherWalter De Gruyter Gmbhen_US
dc.relation.ispartofAsian Biomedicineen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectanemiaen_US
dc.subjectsickle cellen_US
dc.subjectanti-thyroid autoantibodiesen_US
dc.subjectelasticity imaging techniquesen_US
dc.subjectthyroid glanden_US
dc.titleUltrasonographic shear wave elastography of the thyroid in patients with sickle cell anemiaen_US
dc.typeArticleen_US

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
Küçük Resim
İsim:
7669.pdf
Boyut:
755 KB
Biçim:
Adobe Portable Document Format
Açıklama:
Tam Metin / Full Text
İndir

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu