Assessment of Gastroesophageal Reflux Disease in Chronic Obstructive Pulmonary Disease: Is Measuring Cardioesophageal Angle on Multidetector Computed Tomography Images Useful?

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dc.authoridKacar, Emre/0000-0001-7889-6458
dc.contributor.authorUnlu, Ebru
dc.contributor.authorUlasli, Sevinc S.
dc.contributor.authorKacar, Emre
dc.contributor.authorAcay, Mehtap B.
dc.contributor.authorOzdinc, Serife
dc.contributor.authorAtci, Nesrin
dc.contributor.authorBalcik, Cinar
dc.date.accessioned2024-09-18T20:06:32Z
dc.date.available2024-09-18T20:06:32Z
dc.date.issued2016
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractWe aimed to investigate whether there were any differences between patients with chronic obstructive pulmonary disease (COPD) and controls according to their cardioesophageal angles (COA) by Computed tomography (CT) and also the relationship between the degrees of COA and pulmonary function values in COPD patients. Degrees of COA were measured on curved oblique coronal CT images of 198 COPD patients with gastroesophageal reflux (GER) and 298 control subjects. A comparative analysis of COA values in two groups was performed and possible correlations between degrees of COA and pulmonary function parameters were evaluated. COA values were significantly higher in COPD patients compared to controls (p<0.001). The degrees of COA was negatively correlated with FVC and FEV1 values (% and L) in COPD patients (p< 0.001, r=-0.579; p<0.001, r=-0.64 and p<0.001, r=-0.65; p<0.001, r=-0.615, respectively). A positive correlation between age and COA was found in all the study population (p=0.002; r=0.134). A negative correlation between COA and BMI was found in COPD patients (p=0.037, r=-0.149). In conclusion, COPD patients have significantly increased COA value which is a predisposing factor for GER. Also, the association between obtuse COA and decreased levels of pulmonary function parameters in COPD patients may indicate reflux-induced bronchoconstriction and should be considered in COPD management as a non invasive indicator of reflux.en_US
dc.identifier.doi10.2174/1573405611666150930000407
dc.identifier.endpage224en_US
dc.identifier.issn1573-4056
dc.identifier.issn1875-6603
dc.identifier.issue3en_US
dc.identifier.scopus2-s2.0-84975706678en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage220en_US
dc.identifier.urihttps://doi.org/10.2174/1573405611666150930000407
dc.identifier.urihttps://hdl.handle.net/20.500.12483/8565
dc.identifier.volume12en_US
dc.identifier.wosWOS:000384719200009en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherBentham Science Publ Ltden_US
dc.relation.ispartofCurrent Medical Imaging Reviewsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectCardioesophageal angleen_US
dc.subjectchronic obstructive pulmonary diseaseen_US
dc.subjectcomputed tomographyen_US
dc.subjectgastroesophageal refluxen_US
dc.subjectmultiplanar reconstructionen_US
dc.subjectnon-invasive diagnostic toolsen_US
dc.subjectpulmonary function testsen_US
dc.titleAssessment of Gastroesophageal Reflux Disease in Chronic Obstructive Pulmonary Disease: Is Measuring Cardioesophageal Angle on Multidetector Computed Tomography Images Useful?en_US
dc.typeArticleen_US

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