Evaluation of systemic immune-inflammation index level as a novel marker for severity of noninfectious uveitis

Basit Öğe Kaydı
dc.contributor.authorKurtul, Bengi Ece
dc.contributor.authorCakmak, Ayse Idil
dc.contributor.authorElbeyli, Ahmet
dc.contributor.authorOzcan, Sait Coskun
dc.contributor.authorOzcan, Deniz Ozarslan
dc.contributor.authorKimyon, Gezmis
dc.date.accessioned2024-09-18T21:00:30Z
dc.date.available2024-09-18T21:00:30Z
dc.date.issued2021
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractPurpose To evaluate the association of systemic immune-inflammation index (SII) levels, neutrophil/lymphocyte ratio (NLR), and platelet/lymphocyte ratio (PLR) with severity of noninfectious uveitis. Methods This retrospective study included 46 patients with noninfectious uveitis (uveitis group) and 46 age- and sex-matched healthy subjects (control group). The demographic and ocular findings, localization, and activity of uveitis were recorded at the time of onset evaluation. SII, NLR, and PLR levels of patients were compared between the groups. Results SII, NLR, and PLR levels were significantly higher in uveitis group when compared to control group (p < 0.001, p = 0.005, and p = 0.001, respectively). While SII and NLR were significantly higher in severe anterior uveitis than mild anterior uveitis (p = 0.006 and p = 0.021, respectively), only SII was significantly higher in severe posterior and panuveitis than mild ones (p = 0.038). Conclusion SII, as a novel inflammation index, may be more significant tool than NLR and PLR in determining the severity of the uveitis. Furthermore, SII may be a potential useful index in clinical practice to follow-up and manage these patients by monitoring response to anti-inflammatory treatment modalities.en_US
dc.identifier.doi10.1007/s10792-021-01924-9
dc.identifier.endpage3622en_US
dc.identifier.issn0165-5701
dc.identifier.issn1573-2630
dc.identifier.issue11en_US
dc.identifier.pmid34432177en_US
dc.identifier.scopus2-s2.0-85113406623en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage3615en_US
dc.identifier.urihttps://doi.org/10.1007/s10792-021-01924-9
dc.identifier.urihttps://hdl.handle.net/20.500.12483/12731
dc.identifier.volume41en_US
dc.identifier.wosWOS:000688359900001en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.relation.ispartofInternational Ophthalmologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectUveitisen_US
dc.subjectSystemic immune-inflammation indexen_US
dc.subjectNeutrophilen_US
dc.subjectlymphocyte ratioen_US
dc.subjectPlateleten_US
dc.subjectlymphocyte ratioen_US
dc.subjectSeverityen_US
dc.titleEvaluation of systemic immune-inflammation index level as a novel marker for severity of noninfectious uveitisen_US
dc.typeArticleen_US

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
[ N/A ]
İsim:
Tam Metin / Full Text
Boyut:
511.44 KB
Biçim:
Adobe Portable Document Format
İndir

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu