Endobronchial metastases from extrathoracic malignancies

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dc.contributor.authorAkoglu, S
dc.contributor.authorUçan, ES
dc.contributor.authorÇelik, G
dc.contributor.authorSener, G
dc.contributor.authorSevinç, C
dc.contributor.authorKilinç, O
dc.contributor.authorItil, O
dc.date.accessioned2024-09-18T20:16:51Z
dc.date.available2024-09-18T20:16:51Z
dc.date.issued2005
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractEndobronchial metastases (EBM) from extrapulmonary malignant tumors are rare. The most common extrathoracic malignancies associated with EBM are breast, renal and colorectal carcinomas. In this study, we aimed to evaluate the clinical, radiographic and bronchoscopic aspects of patients with EBM who were diagnosed between 1992 and 2002. Data about patients' clinical conditions, symptoms, radiographic and endoscopic findings, and histopathological examination results were investigated. EBM was defined as bronchoscopically visible lesions histopathologically identical to the primary tumor in patients with extrapulmonary malignancies. We found 15 cases with EBM. Primary tumors included breast (3), colorectal (3), and renal (2) carcinomas; Malignant Melanoma (2); synovial sarcoma (1), ampulla of Vater adenocarcinoma (1), pheochromocytoma (1), hypernephroma (1), and Hodgkin's Disease (1). The most common symptoms were dyspnea (80%), cough (66.6%) and hemoptysis (33.3%). Multiple (40%) or single (13.3%) pulmonary nodules, mediastinal or hilar lymphadenopathy (40%), and effusion (40%) were the most common radiographic findings. The mean interval from initial diagnosis to diagnosis of EBM was 32.8 months (range, 0-96 months) and median survival time was 18 months (range, 4-84). As a conclusion, various extrapulmonary tumors can metastasize to the bronchus. Symptoms and radiographic findings are similar with those in primary lung cancer. Therefore, EBM should be discriminated from primary lung cancer histopathologically. Although mean survival time is usually short, long-term survivors were reported. Consequently, treatment must be planned according to the histology of the primary tumor, evidence of metastasis to other sites and medical status of the patient.en_US
dc.identifier.doi10.1007/s10585-005-5787-x
dc.identifier.endpage591en_US
dc.identifier.issn0262-0898
dc.identifier.issue7en_US
dc.identifier.pmid16475029en_US
dc.identifier.scopus2-s2.0-32544433437en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage587en_US
dc.identifier.urihttps://doi.org/10.1007/s10585-005-5787-x
dc.identifier.urihttps://hdl.handle.net/20.500.12483/9778
dc.identifier.volume22en_US
dc.identifier.wosWOS:000235303800008en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.relation.ispartofClinical & Experimental Metastasisen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectendobronchialen_US
dc.subjectendobronchial metastasisen_US
dc.subjectmalignancy metastasisen_US
dc.subjectmetastasisen_US
dc.subjectpulmonary metastasisen_US
dc.titleEndobronchial metastases from extrathoracic malignanciesen_US
dc.typeArticleen_US

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