Beyond expectations: disease duration and psychological burden in psoriatic arthritis

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dc.authoridYurdakul, Ozan Volkan/0000-0003-4567-8133
dc.authoridKILIC, GAMZE/0000-0003-1998-0988
dc.authoridOrhan, Kevser/0000-0001-8639-751X
dc.authoridcuzdan balta, nihan/0000-0001-7238-657X
dc.authoridAcer Kasman, Sevtap/0000-0002-4805-0555
dc.authoridTEKEOGLU, IBRAHIM/0000-0003-3395-7178
dc.authoridNAS, Kemal/0000-0002-5845-0851
dc.contributor.authorKilic, Gamze
dc.contributor.authorKilic, Erkan
dc.contributor.authorTekeoglu, Ibrahim
dc.contributor.authorSargin, Betul
dc.contributor.authorCengiz, Gizem
dc.contributor.authorBalta, Nihan Cuzdan
dc.contributor.authorAlkan, Hakan
dc.date.accessioned2024-09-18T20:02:32Z
dc.date.available2024-09-18T20:02:32Z
dc.date.issued2023
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractThis study aims to investigate the relationship between disease duration and psychological burden in PsA and to identify the risk factors associated with psychological distress. Patients with PsA who met CASPAR classification criteria enrolled by Turkish League Against Rheumatism (TLAR)-Network. Patients were categorized into three groups based on disease duration: early stage (< 5 years), middle stage (& GE; 5, < 10 years), and late stage (& GE; 10 years). All patients underwent clinical and laboratory assessment using standardized protocol and case report forms. The associations between psychological variables and clinical parameters were assessed by a multivariate analysis. Of the 1113 patients with PsA (63.9% female), 564 (%50.7) had high risk for depression and 263 (%23.6) for anxiety. The risk of psychological burden was similar across all PsA groups, and patients with a higher risk of depression and anxiety also experienced greater disease activity, poorer quality of life, and physical disability. Multivariate logistic regression revealed that female gender (OR = 1.52), PsAQoL (OR = 1.13), HAQ (OR = 1.99), FiRST score (OR = 1.14), unemployment/retired (OR = 1.48) and PASI head score (OR = 1.41) were factors that influenced the risk of depression, whereas the current or past enthesitis (OR = 1.45), PsAQoL (OR = 1.19), and FiRST score (OR = 1.26) were factors that influenced the risk of anxiety. PsA patients can experience a comparable level of psychological burden throughout the course of their disease. Several socio-demographic and disease-related factors may contribute to mental disorders in PsA. In the present era of personalized treatment for PsA, evaluating psychiatric distress can guide tailored interventions that improve overall well-being and reduce disease burden.en_US
dc.identifier.doi10.1007/s00296-023-05379-2
dc.identifier.issn0172-8172
dc.identifier.issn1437-160X
dc.identifier.pmid37418001en_US
dc.identifier.scopus2-s2.0-85164103430en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.urihttps://doi.org/10.1007/s00296-023-05379-2
dc.identifier.urihttps://hdl.handle.net/20.500.12483/7845
dc.identifier.wosWOS:001024953900001en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSpringer Heidelbergen_US
dc.relation.ispartofRheumatology Internationalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAnxietyen_US
dc.subjectArthritisen_US
dc.subjectPsoriaticen_US
dc.subjectDepressionen_US
dc.subjectRheumatic diseasesen_US
dc.subjectQuality of lifeen_US
dc.titleBeyond expectations: disease duration and psychological burden in psoriatic arthritisen_US
dc.typeArticleen_US

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