Optimal Timing of Valve Replacement in Asymptomatic Severe Aortic Stenosis

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dc.contributor.authorBilen, Emine
dc.contributor.authorIpek, Gokurk
dc.contributor.authorAyhan, Huseyin
dc.contributor.authorNacar, Alper Bugra
dc.contributor.authorKasapkara, Haci Ahmet
dc.contributor.authorSari, Cenk
dc.contributor.authorBasbug, Serdar
dc.date.accessioned2024-09-18T21:07:54Z
dc.date.available2024-09-18T21:07:54Z
dc.date.issued2014
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractPatients with asymptomatic severe aortic stenosis (AS) constitute a heterogeneous group which includes not only certain cases who are at high risk of sudden death and valve-related heart failure, but also those at low risk for these events. Degenerative AS, which includes a majority of patients with AS, is characterized by stricture of the valve, increased arterial stiffness, and diverse left ventricular response to the valvular plus arterial vascular load. In addition to using traditional primary parameters, the severity of AS and the total left ventricular load should be assessed using new measures such as energy loss index and valvulo-arterial impedance. Natriuretic peptide levels and global longitudinal strain imaging may also be used as secondary parameters to obtain information about left ventricular systolic function, although these parameters do not correlate with the severity of AS. Exercise stress testing and exercise echocardiography are also beneficial when assessing the patient if they are symptomatic, and for determining valvular and left ventricular contractile reserves. The aim of this review was to emphasize the importance of risk stratifications in asymptomatic severe AS cases, and to assess the severity of AS using not only conventional methods but also new methods on which much emphasis has been placed during recent years.en_US
dc.identifier.endpage533en_US
dc.identifier.issn0966-8519
dc.identifier.issue5en_US
dc.identifier.pmid25799699en_US
dc.identifier.startpage524en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12483/14025
dc.identifier.volume23en_US
dc.identifier.wosWOS:000349573100001en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherI C R Publishersen_US
dc.relation.ispartofJournal of Heart Valve Diseaseen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectNonsurgically Managed Patientsen_US
dc.subjectPreserved Ejection Fractionen_US
dc.subjectLeft-Ventricular Mechanicsen_US
dc.subjectValvular Heart-Diseaseen_US
dc.subjectRisk Stratificationen_US
dc.subjectNatriuretic-Peptidesen_US
dc.subjectStress Echocardiographyen_US
dc.subjectPrognostic Valueen_US
dc.subjectNatural-Historyen_US
dc.subjectExerciseen_US
dc.titleOptimal Timing of Valve Replacement in Asymptomatic Severe Aortic Stenosisen_US
dc.typeReview Articleen_US

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