Systemic immune-inflammation index predicts no-reflow phenomenon after primary percutaneous coronary intervention

dc.authoridYamanturk, Yakup Yunus/0000-0003-2636-4710
dc.authoridTan, Turkan Seda/0000-0002-9349-3371
dc.contributor.authorEsenboga, Kerim
dc.contributor.authorKurtul, Alparslan
dc.contributor.authorYamanturk, Yakup Yunus
dc.contributor.authorTan, Turkan Seda
dc.contributor.authorTutar, Durmus Eralp
dc.date.accessioned2024-09-18T19:50:19Z
dc.date.available2024-09-18T19:50:19Z
dc.date.issued2022
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractObjective Systemic immune-inflammation index (SII), on the basis of lymphocyte, neutrophil and platelet counts had been published to be a good prognostic factor in coronary artery disease. Nevertheless, the prognostic value of Systemic immune-inflammation index (SII) in a condition of no-reflow phenomenon (NRP) remains inconsistent, we evaluated the SII as a simple calculated tool for predicting the NRP among patients with STEMI who underwent primary percutaneus coronary intervention (PCI). Method 510 consecutive acute STEMI patients who underwent primary PCI within 12 h from symptom onset from October 2015 to January 2020 were enrolled in our study. The receiver-operating characteristic (ROC) curve was used to determine the cut-off value of SII to predict the no-reflow. Multivariate stepwise logistic regression, including covariates found to have a significant association with NRP in univariate analysis, was used to identify independent predictors of no-reflow. Results A ROC curve analysis showed that the best cut-off value of SII for predicting no-reflow was 1028, with sensitivity and specificity of 79% and 70, respectively (AUC, 0.839; 95% CI 0.797-0.881). An ROC curve comparison analysis was performed to compare the SII with NLR and PLR. Multivariate analysis revealed that SII >= 1028 value (OR = 6.622, 95% confidence interval (CI): 3.802-11.627, p < .001), not using aspirin prior to admission (OR = 0.431, 95%CI: 0.236-0.786, p = .006), and CRP (OR = 1.004, 95%CI: 1.001-1.008, p = .041) were independent predictors related to occurrence of NRP after primary PCI in patients with acute STEMI. Conclusion SII levels are independently associated with the NRP in patients undergoing primary PCI for acute STEMI. High SII may be a promising indicator for the prediction of NRP in these patients.en_US
dc.identifier.doi10.1080/00015385.2021.1884786
dc.identifier.endpage65en_US
dc.identifier.issn0001-5385
dc.identifier.issn1784-973X
dc.identifier.issue1en_US
dc.identifier.pmid33612077en_US
dc.identifier.scopus2-s2.0-85101203729en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage59en_US
dc.identifier.urihttps://doi.org/10.1080/00015385.2021.1884786
dc.identifier.urihttps://hdl.handle.net/20.500.12483/7358
dc.identifier.volume77en_US
dc.identifier.wosWOS:000620516500001en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTaylor & Francis Ltden_US
dc.relation.ispartofActa Cardiologicaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAcute coronary syndromeen_US
dc.subjectST segment elevationen_US
dc.subjectsystemic immune-inflammation indexen_US
dc.subjectthrombus burdenen_US
dc.subjectno-reflow phenomenonen_US
dc.titleSystemic immune-inflammation index predicts no-reflow phenomenon after primary percutaneous coronary interventionen_US
dc.typeArticleen_US

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