Screening various Yarrowia lipolytica strains for citric acid production

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dc.authoridCARSANBA, ERDEM/0000-0002-7218-5070
dc.authoridErten, Huseyin/0000-0003-1537-2416
dc.authoridFickers, Patrick/0000-0002-2600-5833
dc.contributor.authorCarsanba, Erdem
dc.contributor.authorPapanikolaou, Seraphim
dc.contributor.authorFickers, Patrick
dc.contributor.authorErten, Huseyin
dc.date.accessioned2024-09-18T20:04:20Z
dc.date.available2024-09-18T20:04:20Z
dc.date.issued2019
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractCitric acid (CA) productivity by Yarrowia lipolytica dependents on strain type, carbon source, carbon to nitrogen (C/N) molar ratio as well as physicochemical conditions (pH, temperature, oxygen transfer rate, etc.). In the current study, 10 different Y. lipolytica strains were first challenged in shake-flask culture for CA production in a glucose-based media under nitrogen-limited conditions. For the most promising one, strain K57, CA productivity was monitored during culture in batch bioreactor for three initial C/N molar ratio (167, 367, and 567 Cmol/Nmol). The highest CA yield (0.77 g/g glucose), titre (72.3 g/L CA), and productivity (0.04 g/g.h) were found for C/N ratio of 367. However, the highest growth rate was obtained for an initial C/N ratio of 167. From these results, Y. lipolytica strain K57 could be considered to produce CA at higher titre on glucose-based medium in batch bioreactor than others Y. lipolytica strain reported in the literature.en_US
dc.description.sponsorshipScientific Research Projects of Cukurova University, Turkey (BAP) [FDK-2014-3159]; Cukurova University [FDK-2014-3159]en_US
dc.description.sponsorshipThe Scientific Research Projects of Cukurova University, Turkey (BAP), Grant/Award Number: Project Number: FDK-2014-3159; Cukurova University, Grant/Award Number: FDK-2014-3159en_US
dc.identifier.doi10.1002/yea.3389
dc.identifier.endpage327en_US
dc.identifier.issn0749-503X
dc.identifier.issn1097-0061
dc.identifier.issue5en_US
dc.identifier.pmid30945772en_US
dc.identifier.scopus2-s2.0-85067236275en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage319en_US
dc.identifier.urihttps://doi.org/10.1002/yea.3389
dc.identifier.urihttps://hdl.handle.net/20.500.12483/8089
dc.identifier.volume36en_US
dc.identifier.wosWOS:000471600700008en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.ispartofYeasten_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectbatch bioreactor cultureen_US
dc.subjectCen_US
dc.subjectN molar ratioen_US
dc.subjectcitric aciden_US
dc.subjectYarrowia lipolyticaen_US
dc.titleScreening various Yarrowia lipolytica strains for citric acid productionen_US
dc.typeArticleen_US

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