Investigation of Bisphenol A as an endocrine disruptor, total thiol, malondialdehyde, and C-reactive protein levels in chronic obstructive pulmonary disease

Basit Öğe Kaydı
dc.authoridSungur, Sana/0000-0001-7370-8972
dc.authoridOktar, Suleyman/0000-0003-0151-5981
dc.authoridYAKAR, Yasin/0000-0003-3297-3379
dc.contributor.authorErden, E. S.
dc.contributor.authorMotor, S.
dc.contributor.authorUstun, I.
dc.contributor.authorDemirkose, M.
dc.contributor.authorYuksel, R.
dc.contributor.authorOkur, R.
dc.contributor.authorOktar, S.
dc.date.accessioned2024-09-18T20:04:32Z
dc.date.available2024-09-18T20:04:32Z
dc.date.issued2014
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractOBJECTIVE: Chronic obstructive pulmonary disease (COPD) is a common health problem and it is associated with oxidant/antioxidant imbalance and systemic inflammation. Bisphenol A (BPA) is an endocrine disruptor agent, exerting a wide variety of metabolic effects. Also, BPA is related with oxidative stress, decreased antioxidant enzymes, and inflammation. The aim of this study is to investigate the relationships between COPD and serum BPA, Creactive protein (CRP), malondialdehyde (MDA), and total thiol levels. PATIENTS AND METHODS: This study was enrolled at 83 subjects that they were divided into two groups: control (n = 33), COPD (n = 50). The serum BPA, CRP, MDA, and total thiol levels were analyzed. RESULTS: The CRP and BPA levels were significantly higher in the COPD patients than control subjects. The total thiol levels were significantly lower in COPD cases than the controls. There is no different between groups for MDA. Also, there had a linear relationship between BPA and CRP in correlation analysis. CONCLUSIONS: COPD is associated with high serum BPA, CRP and low total thiol levels in comparison with healthy individuals. It is suggested that BPA might have a role in the etiopathogenesis of COPD.en_US
dc.identifier.endpage3483en_US
dc.identifier.issn1128-3602
dc.identifier.issue22en_US
dc.identifier.pmid25491624en_US
dc.identifier.scopus2-s2.0-84937706128en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage3477en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12483/8232
dc.identifier.volume18en_US
dc.identifier.wosWOS:000352210500019en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherVerduci Publisheren_US
dc.relation.ispartofEuropean Review For Medical and Pharmacological Sciencesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectBisphenol Aen_US
dc.subjectChronic obstructive pulmonary diseaseen_US
dc.subjectC-reactive proteinen_US
dc.subjectMalondialdehydeen_US
dc.subjectThiolsen_US
dc.titleInvestigation of Bisphenol A as an endocrine disruptor, total thiol, malondialdehyde, and C-reactive protein levels in chronic obstructive pulmonary diseaseen_US
dc.typeArticleen_US

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
[ N/A ]
İsim:
Tam Metin / Full text
Boyut:
169.86 KB
Biçim:
Adobe Portable Document Format
İndir

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu