The Effect of Slime Factor in the Treatment of Spinal Implant Infections

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dc.contributor.authorTurkoglu, Hasan
dc.contributor.authorKesilmez, Emrullah Cem
dc.contributor.authorSecinti, Kutsal Devrim
dc.contributor.authorSecinti, Ilke Evrim
dc.contributor.authorKucuk, Burak
dc.contributor.authorAral, Murat
dc.contributor.authorEken, Recep
dc.date.accessioned2024-09-18T20:04:28Z
dc.date.available2024-09-18T20:04:28Z
dc.date.issued2024
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractAIM: To investigate the effect of the biofilm-forming ability of the bacteria on treatment in rats by using biofilm-forming and nonbiofilm-forming strains of Staphylococcus aureus (S. aureus). MATERIAL and METHODS: Forty rats were divided into four equal groups as Group 1A, 1B, 2A, and 2B. All rats underwent single distance lumbar laminectomy, and titanium implants were introduced. Group 1 rats were inoculated with Slime factor (-) S. aureus, while Group 2 rats were inoculated with biofilm Slime factor (+) S. aureus. None of the rats were given antibiotics. One week later, the surgical field was reopened and microbiological samples were taken. The implants of rats in Groups 1A and 2A were left in place, while the implants of rats in Groups 1B and 2B were removed. RESULTS: There was no statistically significant difference between the groups inoculated with slime factor (+) S. aureus; although, Groups 1A and 2A showed statistically significant difference. Statistical analysis with respect to bacterial count also showed a statistically significant difference between Groups 1A and 2A. There was a statistically significant difference between Group 1B and CONCLUSION: The results obtained in the present study reveal that in case of implant-dependent infection, the first sample taken can be checked for slime factor, and if there is infection with slime factor-negative bacterium, treatment without removing the implant may be recommended. S. aureus was used in the study because it is the most common cause of implant-related infection at surgical sites. Further studies using different bacterial species are needed to reach a definitive conclusion.en_US
dc.identifier.doi10.5137/1019-5149.JTN.43753-23.1
dc.identifier.endpage474en_US
dc.identifier.issn1019-5149
dc.identifier.issue3en_US
dc.identifier.pmid38650565en_US
dc.identifier.scopus2-s2.0-85193107690en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage468en_US
dc.identifier.urihttps://doi.org/10.5137/1019-5149.JTN.43753-23.1
dc.identifier.urihttps://hdl.handle.net/20.500.12483/8189
dc.identifier.volume34en_US
dc.identifier.wosWOS:001234815200002en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTurkish Neurosurgical Socen_US
dc.relation.ispartofTurkish Neurosurgeryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectBiofilm layeren_US
dc.subjectSlime factoren_US
dc.subjectImplanten_US
dc.subjectRaten_US
dc.titleThe Effect of Slime Factor in the Treatment of Spinal Implant Infectionsen_US
dc.typeArticleen_US

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