The cytogenetic effects of the aqueous extracts of migratory locust ( Locusta migratoria L.) in vitro
Yükleniyor...
Tarih
2014
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Sage Publications Inc
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
One of the useful and most commonly cultivated commercially species, migratory locust (Locusta migratoria; Orthoptera), was investigated in light of genotoxic damage potentials. For this aim, we evaluated the genotoxic potentials of water soluble extracts of L. migratoria on cultured human blood cells. The micronucleus, sister chromatid exchange and structural chromosome aberration assays were applied to assess DNA and chromosomal damage produced by aqueous extracts in vitro. The extracts were added to the cultures at different concentrations ranging from 0 to 1000mg/L. Our results indicated that these extracts did not exhibit genotoxicity at tested concentrations. We conclude that this in vitro approach for biomonitoring genotoxicity assessment is useful for comparing the potential health risks of edible insects.
Açıklama
Anahtar Kelimeler
Chromosome aberration, genotoxicity, human lymphocytes, Locusta migratoria, micronucleus, sister chromatid exchange
Kaynak
Toxicology and Industrial Health
WoS Q Değeri
Q2
Scopus Q Değeri
Q2
Cilt
30
Sayı
3
