ANTIFUNGAL ACTIVITY OF Origanum syriacum L. ESSENTIAL OILS AGAINST Candida spp.

Basit Öğe Kaydı
dc.authoridKaya, Durmus Alpaslan/0000-0003-3544-9214
dc.contributor.authorDuran, Nizami
dc.contributor.authorKaya, Durmus Alpaslan
dc.date.accessioned2024-09-18T20:06:25Z
dc.date.available2024-09-18T20:06:25Z
dc.date.issued2018
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description7th International Conference on Advanced Materials and Systems -- OCT 18-20, 2018 -- Bucharest, ROMANIAen_US
dc.description.abstractThe infections caused by Candida species have been reported to cause serious life-threatening infections. Because the increased drug resistance among candida spp., new drug researches are intensively carried out. Origanum syriacum L. is a valuable medicinal plant in terms of its components. The aim of this study was to investigate components and the antifungal activity of Origanum syriacum L. essential oils on the growth of Candida spp. By GC-MS was highlighted that thymol (42,18 %), carvacrol (33,95 %), cymene (8,87 %) and gamma-terpinene (8,21 %) are the main components. Antifungal activity of the essential oils of Origanum syriacum L. was evaluated by microdilution method. The most notable activity was obtained against C. dubliniensis, C. albicans and C. parapsilosis. MIC values were found to be 15.6 C. for C. dubliniensis and 31.2 mu g/ml for C. parapsilosis and C. albicans. MIC values against C. glabrata, C. kern., C. intermedia were found to be 62.5, MIC values for C. krusei and C. glabrata were 125 mu g/ml. The highest activity in terms of MBC values in the study was obtained against C. intermedia and C. parapsilosis (62.5 mu g/ml). Our results are particularly promising to have significant activity against C. dubliniensis, C. albicans and C. parapsilosis. Origanum syriacum L. essential oils, which were also effective against non-albicans Candida species, may be a new hope for the treatment of candida infections.en_US
dc.description.sponsorshipMinist Res & Innovat,Natl Res & Dev Inst Textile & Leather, Div Leather & Footwear Res Insten_US
dc.identifier.doi10.24264/icams-2018.I.11
dc.identifier.endpage85en_US
dc.identifier.scopus2-s2.0-85087988983en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage81en_US
dc.identifier.urihttps://doi.org/10.24264/icams-2018.I.11
dc.identifier.urihttps://hdl.handle.net/20.500.12483/8512
dc.identifier.wosWOS:000464905000011en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherIncdtp-Icpien_US
dc.relation.ispartofProceedings of The 7th International Conference on Advanced Materials and Systemsen_US
dc.relation.publicationcategoryKonferans Öğesi - Uluslararası - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectCandidaen_US
dc.subjectOriganum syriacum L.en_US
dc.subjectessential oilsen_US
dc.subjectantifungalen_US
dc.subjectresistanceen_US
dc.titleANTIFUNGAL ACTIVITY OF Origanum syriacum L. ESSENTIAL OILS AGAINST Candida spp.en_US
dc.typeConference Objecten_US

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