Erythrocyte sedimentation rate in acute myocardial infarction as a predictor of poor prognosis and impaired reperfusion

dc.authoridOzcan, Firat/0000-0002-7954-7839
dc.contributor.authorOzlu, Mehmet Fatih
dc.contributor.authorSen, Nihat
dc.contributor.authorKarakas, Mehmet Fatih
dc.contributor.authorTurak, Osman
dc.contributor.authorOzcan, Firat
dc.contributor.authorKanat, Selcuk
dc.contributor.authorAras, Dursun
dc.date.accessioned2024-09-18T20:59:09Z
dc.date.available2024-09-18T20:59:09Z
dc.date.issued2012
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractAim To investigate whether the elevated erythrocyte sedimentation rate (ESR) is associated with an adverse prognosis in the patients with ST-segment elevation myocardial infarction (STEM I) undergoing primary percutaneous coronary intervention (PCI). Methods It included 140 consecutive patients undergoing primary PCI for acute STEM!, <12 hours after symptom beginning and 50 healthy age and sex matched control subjects. All patients were categorized into two groups defined by the median ESR level on admission. These two groups were compared in terms of myocardial perfusion, and one year outcomes. Results Levels of ESR were higher ill patients with STEM! than in the healthy group. Patients in the elevated ESR group had a higher incidence of impaired angiographic reperfusion compared to patients in the lower ESR group (Mean TIMI frame count; 25.5 +/- 6.5 versus 20.4 +/- 5.2, p<0.01, TMPG 0-2; 55 % versus 29%, p<0.01). In-hospital and one-year mortality rates were significantly higher in patients with higher ESR. In-hospital and one-year MACE rates were significantly greater in elevated ESR group (14%-26), compared to the lower ESR group (4%-13%). Increased ESR levels on admission emerged as independent predictors of long term prognosis. The ROC analysis revealed an optimal cut-point of >= 33 mm/h, detected I year mortality with a negative predictive value of 96%. Conclusion The high admission ESR levels are found to be related with impaired coronary flow in patients undergoing primary PC-I that possibly contribute to poor short- and long-term prognosis. Therefore, admission ESR evaluation may be helpful in identifying patients with a poor prognosis.en_US
dc.identifier.endpage197en_US
dc.identifier.issn1840-0132
dc.identifier.issue2en_US
dc.identifier.pmid22926349en_US
dc.identifier.scopus2-s2.0-84868261030en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage189en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12483/12411
dc.identifier.volume9en_US
dc.identifier.wosWOS:000307479600003en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherMedical Assoc Zenicadoboj Cantonen_US
dc.relation.ispartofMedicinski Glasniken_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectST-segmenten_US
dc.subjectinflammationen_US
dc.subjectmyocardial perfusion gradeen_US
dc.titleErythrocyte sedimentation rate in acute myocardial infarction as a predictor of poor prognosis and impaired reperfusionen_US
dc.typeArticleen_US

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