The Effect of Enoxaparin-Containing Irrigation Fluid Used During Cataract Surgery on Postoperative Inflammation in Patients With Diabetes

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dc.authoridAyintap, Emre/0000-0002-7537-2672
dc.contributor.authorIlhan, Ozgur
dc.contributor.authorIlhan, Nilufer
dc.contributor.authorCoskun, Mesut
dc.contributor.authorDaglioglu, Mutlu Cihan
dc.contributor.authorTuzcu, Esra Ayhan
dc.contributor.authorAyintap, Emre
dc.contributor.authorKeskin, Ugurcan
dc.date.accessioned2024-09-18T21:03:01Z
dc.date.available2024-09-18T21:03:01Z
dc.date.issued2013
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractPURPOSE: To investigate effects of enoxaparin on postoperative inflammation in patients with moderate nonproliferative diabetic retinopathy (NPDR) and nuclear cataract. DESIGN: Prospective masked controlled trial. METHODS: SETTING: Institutional practice. STUDY POPULATION: The study included 51 eyes of 51 diabetes mellitus (DM) patients with moderate NPDR and grade 2-3 nuclear cataracts. Group 1 included randomly selected patients who received enoxaparin in balanced salt solution (BSS) during cataract surgery, while standard BSS was used in Group 2. OBSERVATION PROCEDURE: Patients were followed up 1 day, 1 week, and 1 and 2 months after the surgery. MAIN OUTCOME MEASURES: Anterior chamber cell and flare. RESULTS: Postoperatively, 20 patients from Group 1 and 4 patients in Group 2 had less than a mean of 10 cells at day 1 (P = .012). At the first week, 20 patients from Group 1 and 10 patients from Group 2 had less than a mean of 10 cells (P = .004). When compared for flare, 20 patients from Group 1 and 8 patients from Group 2 had a flare between 0 and + 1 at postoperative day 1 (P < .001). By the end of postoperative first week, 24 patients from Group land 18 patients from Group. 2 had a flare between 0 and + 1 (P = .012). There was no difference between groups in terms of postoperative inflammation at the first and second months after the surgery. CONCLUSION: The results of the study suggest that enoxaparin added into the infusion fluid may reduce postoperative inflammation in patients with DM, and this result supports the anti-inflammatory effect of enoxaparin. ((C) 2013 by Elsevier Inc. All rights reserved.)en_US
dc.identifier.doi10.1016/j.ajo.2013.07.017
dc.identifier.endpage1124en_US
dc.identifier.issn0002-9394
dc.identifier.issn1879-1891
dc.identifier.issue6en_US
dc.identifier.pmid24075427en_US
dc.identifier.scopus2-s2.0-84888007144en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage1120en_US
dc.identifier.urihttps://doi.org/10.1016/j.ajo.2013.07.017
dc.identifier.urihttps://hdl.handle.net/20.500.12483/13203
dc.identifier.volume156en_US
dc.identifier.wosWOS:000327674900008en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherElsevier Science Incen_US
dc.relation.ispartofAmerican Journal of Ophthalmologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectMolecular-Weight Heparinen_US
dc.subjectBlood-Aqueous Barrieren_US
dc.subjectIntraocular Lensesen_US
dc.subjectRetinopathyen_US
dc.subjectSurfaceen_US
dc.subjectPhotocoagulationen_US
dc.subjectExtractionen_US
dc.titleThe Effect of Enoxaparin-Containing Irrigation Fluid Used During Cataract Surgery on Postoperative Inflammation in Patients With Diabetesen_US
dc.typeArticleen_US

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