Collagen Wound Dressings with Anti-Inflammatory Activity
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Tarih
2012
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Taylor & Francis Ltd
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
The aim of this study was to develop modern wound dressings such as controlled drug delivery systems. These systems consist in collagen as release support and niflumic acid as drug. The scaffolds were prepared by lyophilization in order to obtain porous structures and were evaluated by release profile of niflumic acid, water absorption, collagenase degradation and biocompatibility with fibroblast cells. The collagen scaffold with 0.75% niflumic acid solved in laurel oil was optimal in terms of biodegradability, absorbability and fibroblast cells biocompatibility. Thus, the obtained collagen scaffolds could be used as wound dressings with absorbent, antibacterial and anti-inflammatory properties.
Açıklama
Anahtar Kelimeler
Collagen, fibroblast cells, niflumic acid, scaffolds, wound dressing
Kaynak
Molecular Crystals and Liquid Crystals
WoS Q Değeri
Q4
Scopus Q Değeri
Q4
Cilt
555
