The genetic diversity of bovine papillomaviruses (BPV) from different papillomatosis cases in dairy cows in Turkey

Basit Öğe Kaydı
dc.authoridBastan, Ayhan/0000-0001-8291-1147
dc.authoridSalar, Seckin/0000-0001-9303-6253
dc.contributor.authorBilge Dagalp, Seval
dc.contributor.authorDogan, Firat
dc.contributor.authorFarzani, Touraj Alighopour
dc.contributor.authorSalar, Seckin
dc.contributor.authorBastan, Ayhan
dc.date.accessioned2024-09-18T21:02:56Z
dc.date.available2024-09-18T21:02:56Z
dc.date.issued2017
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractPapillomaviruses (PVs) are epitheliotropic viruses that cause benign proliferative lesions in the skin (warts or papillomas) and mucous membranes of their natural hosts. In bovines specifically, 13 types of Bovine papillomaviruses (BPVs) are currently described in the literature, although the actual number may be greater than 20. BPV types are classified into four genera based on homology within the genomic regions of the L1 ORF, the most conserved sequence. This study conducted molecular typing of BPV in dairy cows with different papillomatosis cases and investigated the presence of co-infections across distinct BPV types in the same sample. After carrying out PCR using degenerate primers and type specific primers, 35 BPV suspected samples were detected as positive for BPV and these samples were used for typing using sequence analysis/PCR with type-specific primers. This analysis identified BPV-1, -2, -3, -4, -6, -7, -9 and -10, new putative types (BPV/BR/UEL6-like viruses) and the previously described putative type viruses (BAPV-6) in the 35 BPV-positive samples. In addition, co-infections across different BPV types were widely detected in the BPV-positive samples. This study shows that PCR assays using degenerate primers to amplify partial fragments of the L1 gene followed by sequencing is useful for genotyping BPV. However, results need confirmation using type-specific primers in order to consider co-infections. In addition, this study identified a new putative type (in the same cluster as BPV/BR/UEL6-like viruses) and the previously described putative type viruses (BAPV-6) in teat papillomatosis of Turkish dairy cows. The study shows that it is essential to identify BPV types and their prevalence/distribution, and also to determine the clinical consequences of infection for the development of prophylactic and/or therapeutic procedures.en_US
dc.identifier.doi10.1007/s00705-017-3258-8
dc.identifier.endpage1518en_US
dc.identifier.issn0304-8608
dc.identifier.issn1432-8798
dc.identifier.issue6en_US
dc.identifier.pmid28190198en_US
dc.identifier.scopus2-s2.0-85012134639en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage1507en_US
dc.identifier.urihttps://doi.org/10.1007/s00705-017-3258-8
dc.identifier.urihttps://hdl.handle.net/20.500.12483/13141
dc.identifier.volume162en_US
dc.identifier.wosWOS:000401119300006en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSpringer Wienen_US
dc.relation.ispartofArchives of Virologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectMolecular-Identificationen_US
dc.subjectCutaneous Tumorsen_US
dc.subjectCattleen_US
dc.subjectVirusen_US
dc.subjectWartsen_US
dc.subjectDnaen_US
dc.subjectHealthyen_US
dc.subjectExpressionen_US
dc.subjectType-1en_US
dc.subjectCanceren_US
dc.titleThe genetic diversity of bovine papillomaviruses (BPV) from different papillomatosis cases in dairy cows in Turkeyen_US
dc.typeArticleen_US

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
[ N/A ]
İsim:
Tam Metin / Full Text
Boyut:
1.1 MB
Biçim:
Adobe Portable Document Format
İndir

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu