Perinatal effects of maternal FT3/FT4 ratio on gestational transient thyrotoxicosis

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dc.authoridDIRICAN, EMRE/0000-0003-3550-1326
dc.authoridgurkan, eren/0000-0002-3118-4549
dc.contributor.authorGurkan, Eren
dc.contributor.authorDolapcioglu, Kenan
dc.contributor.authorDirican, Emre
dc.date.accessioned2024-09-18T20:25:22Z
dc.date.available2024-09-18T20:25:22Z
dc.date.issued2021
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractObjective: The effects of maternal thyroid hormone levels on the course of pregnancy and birth weight have attracted interest. The aim of the present study was to consider FT3 and FT3/FT4 ratio in the evaluation of the effects of maternal thyroid functions in gestational transient thyrotoxicosis (GTT). Materials and methods: This case-control study included 45 patients with GTT and 45 healthy pregnant women. Maternal history before pregnancy, thyroid function tests, thyroid autoantibodies, and thyroid ultrasonography results in 6th to 10th weeks of pregnancy were used in the differential diagnosis of GTT. In both groups, the effects of FT3, FT4 and FT3/FT4 ratios on gestational age and birth weight were evaluated. Results: There was no significant difference in the gestational age between the GTT and control groups (39,3 +/- 1,0 weeks and 39,2 +/- 1,2 weeks, respectively). Birth weights were similar in both groups (3205,2 +/- 4899 g and 3196,6 +/- 309,3 g, respectively). When maternal weight was adjusted, a positive correlation was observed between maternal FT3/FT4 ratio and birth weight (r=0,317, p=0,017). Additionally there was a positive correlation between the gestational age and the birth weight in the control group (rho = 0,726, p=0,001). Conclusion: GTT had no significant effect on the gestational age and the birth weight. On the other hand an increase in the maternal FT3/FT4 ratio had a positive effect on the birth weight in the patient with GTT. Maternal characteristics (age, weight, BMI) and FT3/FT4 ratio should be taken into consideration in future impact assessment studies on this issue.en_US
dc.identifier.doi10.20945/2359-3997000000371
dc.identifier.endpage454en_US
dc.identifier.issn2359-3997
dc.identifier.issn2359-4292
dc.identifier.issue4en_US
dc.identifier.pmid34283898en_US
dc.identifier.scopus2-s2.0-85121938927en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage450en_US
dc.identifier.urihttps://doi.org/10.20945/2359-3997000000371
dc.identifier.urihttps://hdl.handle.net/20.500.12483/10266
dc.identifier.volume65en_US
dc.identifier.wosWOS:000701275300008en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSbem-Soc Brasil Endocrinologia & Metabologiaen_US
dc.relation.ispartofArchives of Endocrinology Metabolismen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectGestational transient thyrotoxicosisen_US
dc.subjectmaternal weighten_US
dc.subjectbirth weighten_US
dc.subjectgestational ageen_US
dc.subjectthyroid function testsen_US
dc.titlePerinatal effects of maternal FT3/FT4 ratio on gestational transient thyrotoxicosisen_US
dc.typeArticleen_US

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