Higher Serum Bisphenol A Levels in Diabetic Hemodialysis Patients

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Küçük Resim

Tarih

2016

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

Karger

Erişim Hakkı

info:eu-repo/semantics/closedAccess

Özet

Background: Bisphenol A (BPA) has been implicated as an 'endocrine disruptor'. We aimed at exploring the association between serum BPA levels and patient characteristics, particularly the presence of diabetes mellitus, and laboratory parameters in hemodialysis patients. Methods: This study included 47 chronic hemodialysis patients. Patient characteristics were recorded. Blood was drawn before and after hemodialysis session. Serum BPA levels were measured by the high-performance-liquid-chromatography and laboratory parameters were measured by using standard methods. Results: In hemodialysis patients, postdialysis serum BPA levels were significantly higher than predialysis after a single hemodialysis session (5.57 +/- 1.2 vs. 4.06 +/- 0.73, p < 0.0001). Predialysis serum BPA levels were significantly higher in patients with diabetes than non-diabetics (4.4 +/- 0.6 vs. 3.9 +/- 0.7, p = 0.025). No association was found between serum BPA levels and patient characteristics, and particularly laboratory parameters. Conclusion: Serum BPA levels were rising significantly after a single dialysis session. Diabetic hemodialysis patients had higher predialysis serum BPA levels. (C) 2016 S. Karger AG, Basel

Açıklama

Anahtar Kelimeler

Bisphenol A, Chronic kidney disease, Hemodialysis, Diabetes mellitus

Kaynak

Blood Purification

WoS Q Değeri

Q3

Scopus Q Değeri

Q1

Cilt

42

Sayı

1

Künye