Spuriously high phosphate level which is promptly resolved after plasmapheresis in a patient with multiple myeloma

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dc.contributor.authorKiki, Ilhami
dc.contributor.authorGundogdu, Mehmet
dc.contributor.authorKaya, Hasan
dc.date.accessioned2024-09-18T20:33:00Z
dc.date.available2024-09-18T20:33:00Z
dc.date.issued2007
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractWe present a 57 year old female patient with IgG multiple myeloma and marked hyperphosphatemia. The patient had no clinical symptoms related to hyperphosphatemia. Serum inorganic phosphate measurements were repeated on sulfosalicylic acid deproteinized serum samples, yielding normal phosphate levels. We realized that this hyperphosphatemia was spurious because of high paraprotein levels. Afterwards, therapeutic plasma exchange (TPE) was administered due to hyperviscosity and bleeding tendency. After the administration of TPE, serum phosphate was reduced to normal level. Therapeutic plasma exchange resulted in steady-state serum phosphate levels during the three months follow up period. We concluded that high phosphate levels must be confirmed by measuring in deproteinized serum samples in multiple myeloma patients in order to distinguish pseudohyperphosphatemia from the true ones. In addition, TPE effectively reduces the spuriously elevated phosphate levels possibly by removing paraproteins. (C) 2007 Elsevier Ltd. All rights reserved.en_US
dc.identifier.doi10.1016/j.transci.2007.07.005
dc.identifier.endpage159en_US
dc.identifier.issn1473-0502
dc.identifier.issue2en_US
dc.identifier.pmid18037346en_US
dc.identifier.scopus2-s2.0-36549055513en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage157en_US
dc.identifier.urihttps://doi.org/10.1016/j.transci.2007.07.005
dc.identifier.urihttps://hdl.handle.net/20.500.12483/11261
dc.identifier.volume37en_US
dc.identifier.wosWOS:000252078300009en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherPergamon-Elsevier Science Ltden_US
dc.relation.ispartofTransfusion and Apheresis Scienceen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectmultiple myelomaen_US
dc.subjectpseudohyperphosphatemiaen_US
dc.subjecttherapeutic plasma exchangeen_US
dc.titleSpuriously high phosphate level which is promptly resolved after plasmapheresis in a patient with multiple myelomaen_US
dc.typeArticleen_US

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