Treatment initiation rates of patients with positive anti-hepatitis C virus results in tertiary hospitals in Turkey

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dc.authoridCandevir, Aslihan/0000-0001-9340-516X
dc.authoridSahin, Ahmet Melih/0000-0003-3670-7801
dc.authoridAzap, Alpay/0000-0001-5035-055X
dc.authoridDemirturk, Nese/0000-0002-6186-2494
dc.authoridzerdali, esra/0000-0002-7023-6639
dc.authoridKaya, Safak/0000-0001-9912-7340
dc.contributor.authorCelen, Mustafa K.
dc.contributor.authorSengel, Buket Erturk
dc.contributor.authorKaya, Safak
dc.contributor.authorDemirturk, Nese
dc.contributor.authorAzap, Alpay
dc.contributor.authorPullukcu, Husnu
dc.contributor.authorEroglu, Esma
dc.date.accessioned2024-09-18T20:26:41Z
dc.date.available2024-09-18T20:26:41Z
dc.date.issued2024
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractIntroduction: The aim of this national, multicenter, cross-sectional, retrospective chart review study was to determine the proportion of patients in Turkey who received hepatitis C virus (HCV) treatment after receiving positive anti-HCV results during HCV screening. Methodology: Data related to patients' demographics, laboratory results, time interval from obtaining a positive anti-HCV result to treatment initiation, specialty of the physician requesting anti-HCV screening, and type of hospital were analyzed. Results: Among 1,000 patients who received a positive anti-HCV result, 50.3% were male and 78.5% were screened for HCV-RNA. Among HCV-RNA screened patients, 54.8% (n = 430) had a positive result. Among patients who tested positive for HCV-RNA, 72.8% received HCV treatment in line with their positive anti-HCV results. The median time from obtaining a positive anti-HCV result to initiation of HCV treatment was 91.0 days (interquartile range 42.0 to 178.5). Non -surgical branches requested HCV-RNA testing more frequently than surgical branches (p < 0.001). The rate of access to HCV treatment was higher among patients screened in university hospitals than among patients screened in training and research hospitals (p < 0.001). Conclusions: Our results indicate a higher rate of treatment initiation among patients with HCV infection than is described in the published literature. Furthermore, the time from screening to treatment initiation was considerably shorter compared with other international studies. However, since HCV-RNA testing was not requested in a significant portion of patients with a positive anti-HCV test result, there might be a large patient population with HCV who do not receive treatment.en_US
dc.identifier.doi10.3855/jidc.17910
dc.identifier.endpage449en_US
dc.identifier.issn1972-2680
dc.identifier.issue3en_US
dc.identifier.pmid38635621en_US
dc.identifier.scopus2-s2.0-85191028725en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage441en_US
dc.identifier.urihttps://doi.org/10.3855/jidc.17910
dc.identifier.urihttps://hdl.handle.net/20.500.12483/10479
dc.identifier.volume18en_US
dc.identifier.wosWOS:001208947900001en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherJ Infection Developing Countriesen_US
dc.relation.ispartofJournal of Infection in Developing Countriesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectHepatitis Cen_US
dc.subjectanti-HCVen_US
dc.subjectscreeningen_US
dc.subjecttreatmenten_US
dc.subjectTurkeyen_US
dc.titleTreatment initiation rates of patients with positive anti-hepatitis C virus results in tertiary hospitals in Turkeyen_US
dc.typeArticleen_US

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