Anti-CCP Antibodies Are Not Associated with Familial Mediterranean Fever in Childhood

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dc.authoridonur, hatice/0000-0002-1218-0745
dc.authoridKasapcopur, Ozgur/0000-0002-1125-7720
dc.contributor.authorOnur, Hatice
dc.contributor.authorAral, Hale
dc.contributor.authorArica, Vefik
dc.contributor.authorBercem, Gamze
dc.contributor.authorUsta, Murat
dc.contributor.authorKasapcopur, Ozgur
dc.date.accessioned2024-09-18T21:06:27Z
dc.date.available2024-09-18T21:06:27Z
dc.date.issued2013
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractObjective. Anticyclic citrullinated peptide antibodies (anti-CCP) testing is useful in the diagnosis of rheumatoid arthritis (RA) with high specificity. Arthritis is a very common clinical manifestation in children with familialMediterranean fever (FMF). The aim of the study was to show the presence of anti-CCP antibodies in child individuals diagnosed with FMF. Material and Methods. The study groups comprised one hundred and twenty-six patients (126) diagnosed with FMF (female/male (n): 66/60) and 50 healthy controls (female/male (n): 25/25). Clinical and laboratory assessments of the FMF patients were performed during attack-free periods. Erythrocyte sedimentation rate (ESR), serum C-reactive protein (CRP), fibrinogen, and anti-CCP antibody levels were measured. Results. Anti-CCP was negative in healthy controls and also in all FMF patients. There was not a significant difference in anti-CCP between the patient and the control groups. Our study has shown that anti-CCP was correlated moderately with age (rs = 0.271; p = 0.0020), duration of illness (rs = 0.331; p < 0.0001), and colchicine therapy (rs = 0.259; p = 0.004). Conclusion. Our data show that anti-CCP antibodies are not associated with FMF. Anti-CCP does not have a priority for identifying FMF arthritis from the other inflammatory arthritis.en_US
dc.identifier.doi10.1155/2013/498581
dc.identifier.issn1687-9260
dc.identifier.issn1687-9279
dc.identifier.pmid24106502en_US
dc.identifier.scopus2-s2.0-84884849053en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.urihttps://doi.org/10.1155/2013/498581
dc.identifier.urihttps://hdl.handle.net/20.500.12483/13606
dc.identifier.volume2013en_US
dc.identifier.wosWOS:000214705300012en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherHindawi Ltden_US
dc.relation.ispartofInternational Journal of Rheumatologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectCitrullinated Peptide Antibodiesen_US
dc.subjectDiagnostic-Accuracyen_US
dc.subjectAutoantibodiesen_US
dc.subjectChildrenen_US
dc.titleAnti-CCP Antibodies Are Not Associated with Familial Mediterranean Fever in Childhooden_US
dc.typeArticleen_US

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