Assessment of Red Cell Distribution Width, Platelet/lymphocyte Ratio, Systemic Immune-inflammation Index, and Neutrophil/lymphocyte Ratio Values in Patients with Central Retinal Artery Occlusion

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Küçük Resim

Tarih

2022

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

Taylor & Francis Inc

Erişim Hakkı

info:eu-repo/semantics/closedAccess

Özet

Purpose To evaluate complete blood count (CBC)-derived inflammatory indices in central retinal artery occlusion (CRAO). Methods A total of 42 patients with CRAO (CRAO group) and 42 age- and sex-matched subjects without CRAO (Control group) were included. CBC parameters including red cell distribution width (RDW) levels were assayed. Platelet/lymphocyte ratio (PLR), systemic immune-inflammation index (SII) and neutrophil/ lymphocyte ratio (NLR) were calculated. Results RDW, PLR, SII and NLR values were significantly higher in CRAO group than control group [15.2 +/- 1.47% vs 13.96 +/- 1.13% (p < .001), 127.94 +/- 48.21 vs 101.16 +/- 24.84 (p = .008), 667.11 +/- 357.84 vs 493.44 +/- 207.07 (p = .008), 2.70 +/- 1.27 vs 2.13 +/- 0.83 (p = .018), respectively]. In multivariate analysis only RDW was independent predictor for CRAO (OR 2.317, p < .001). On ROC analysis, area under curve of RDW, PLR, SII, and NLR for CRAO were 0.761, 0.685, 0.622 and 0.618, respectively. Conclusion RDW seems superior to other inflammatory indices to predict CRAO.

Açıklama

Anahtar Kelimeler

Central retinal artery occlusion, blood cell count, red cell distribution width, platelet, lymphocyte ratio, systemic immune-inflammation index, neutrophil, lymphocyte ratio, Inflammation

Kaynak

Ocular Immunology and Inflammation

WoS Q Değeri

Q2

Scopus Q Değeri

Q1

Cilt

30

Sayı

7-8

Künye