Evaluation of epicardial adipose tissue in children with type 1 diabetes

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dc.authoridDEMIRAY, SEYMA/0000-0003-3596-2704
dc.authoridgullu, ufuk utku/0000-0002-5561-3598
dc.authoridtrabzon, gul/0000-0002-9262-5678
dc.authoridCaliskan, Osman Firat/0009-0007-4991-1955
dc.contributor.authorTrabzon, Guel
dc.contributor.authorGungor, Sukru
dc.contributor.authorGullu, Seyma Demiray
dc.contributor.authorCaliskan, Osman Firat
dc.contributor.authorGullu, Ufuk Utku
dc.date.accessioned2024-09-18T21:03:16Z
dc.date.available2024-09-18T21:03:16Z
dc.date.issued2024
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractIntroduction Epicardial adipose tissue (EAT), the visceral fat surrounding the heart between the myocardium and visceral pericardium, intersects with Type 1 diabetes (T1D). This review aims to elucidate the intricate association between EAT and childhood T1D.Materials and methods In this retrospective study, two pediatric groups were involved children with type 1 diabetes, and healthy children. Epicardial fat thickness was measured appropriately, and the study documented HbA1c levels and time to diabetes diagnosis for comprehensive analysis.Results Encompassing 51 children with T1D and 69 healthy controls, revealed that children with type 1 diabetes had a mean HbA1c level of 9.4 +/- 0.2, and a mean insulin dose of 0.94 units/kg/day. Epicardial adipose tissue (EAT) values were significantly higher in the Type 1 DM group. It has been shown that epicardial fat thickness may have a specific and sensitive value in type 1 diabetics.Discussion The increased presence of epicardial fat tissue in children with type 1 diabetes is highlighted, prompting the consideration of various mechanisms. However, the complexity of this relationship underscores the need for further studies to provide a more comprehensive understanding of the underlying factors. Ongoing research in this area is crucial for advancing our knowledge and potential therapeutic interventions.Impacts Cardiac complications are one of the most important causes of morbidity and mortality in people with type 1 diabetes. Being able to detect cardiological complications of diabetes at an early stage contributes to morbidity. We found that epicardial fat tissue thickness was thicker in children with type 1 diabetes than in healthy children. Epicardial fat tissue thickness may be associated with poor control in children with type 1 diabetes and maybe a guide in terms of cardiac risks.en_US
dc.description.sponsorshipScientific and Technological Research Council of Turkiye (TUBITAK)en_US
dc.description.sponsorshipThis research was not financially supported by any pharmaceutical companies, medical device manufacturers, or other commercial entities that could potentially benefit from the outcomes of this study. All analyses and interpretations of the data were carried out independently by the authors. Open access funding provided by the Scientific and Technological Research Council of Turkiye (TUBITAK).en_US
dc.identifier.doi10.1038/s41390-024-03319-9
dc.identifier.issn0031-3998
dc.identifier.issn1530-0447
dc.identifier.pmid38879626en_US
dc.identifier.scopus2-s2.0-85196069716en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.urihttps://doi.org/10.1038/s41390-024-03319-9
dc.identifier.urihttps://hdl.handle.net/20.500.12483/13334
dc.identifier.wosWOS:001248309700003en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSpringernatureen_US
dc.relation.ispartofPediatric Researchen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectFaten_US
dc.titleEvaluation of epicardial adipose tissue in children with type 1 diabetesen_US
dc.typeArticleen_US

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