Vitamin D status in patients with rosacea

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dc.contributor.authorEkiz, Ozlem
dc.contributor.authorBalta, Ilknur
dc.contributor.authorSen, Bilge Bulbul
dc.contributor.authorDikilitas, Meltem Cik
dc.contributor.authorOzuguz, Pinar
dc.contributor.authorRifaioglu, Emine Nur
dc.date.accessioned2024-09-18T20:08:05Z
dc.date.available2024-09-18T20:08:05Z
dc.date.issued2014
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description.abstractBackground: Rosacea is a common chronic skin condition affecting the face. In recent years, significant evidence shows that vitamin D plays an important role in modulating the immune system. Vitamin D and its analogues via these mechanisms are playing an increasing role in the management of atopic dermatitis, psoriasis, vitiligo, acne and rosacea. Objectives: In our study, we aimed to investigate the relationship between serum vitamin D levels in patients with rosacea and analyze the association of vitamin D with clinical features. Methods: Forty-four rosacea patients and 32 healthy control subjects were included into the study. 25-hydroxyvitamin D (25(OH)D), calcium and intact parathyroid hormone were measured. Deficiency of vitamin D is defined as the level of 25(OH)D being less than 20 ng/ml. Results: Thirty-three female and 11 male patients were included in the study. The mean age of patients was 48.6 +/- 11.5. The mean levels of vitamin D levels were found as 21.4 +/- 9.9 and 17.1 +/- 7.9 in patients and controls, respectively. The difference was statistically significant (p = 0.04). The prevalence of vitamin D deficiency in patients with rosacea was 38.6% and 28.1% in healthy controls (p = 0.34). Conclusions: To the best of our knowledge, our study is the first study for evaluating serum vitamin D levels of patients with rosacea in the literature. Patients with rosacea have relatively high serum vitamin D levels compared to control groups. The result of our study suggests that increased vitamin D levels may lead to the development of rosacea. To confirm status of vitamin D levels in patients with rosacea, larger epidemiological studies are needed.en_US
dc.identifier.doi10.3109/15569527.2013.797907
dc.identifier.endpage62en_US
dc.identifier.issn1556-9527
dc.identifier.issn1556-9535
dc.identifier.issue1en_US
dc.identifier.pmid23713748en_US
dc.identifier.scopus2-s2.0-84894365005en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage60en_US
dc.identifier.urihttps://doi.org/10.3109/15569527.2013.797907
dc.identifier.urihttps://hdl.handle.net/20.500.12483/8623
dc.identifier.volume33en_US
dc.identifier.wosWOS:000331847200011en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTaylor & Francis Ltden_US
dc.relation.ispartofCutaneous and Ocular Toxicologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectCathelicidinen_US
dc.subjectrosaceaen_US
dc.subjectvitamin D levelsen_US
dc.titleVitamin D status in patients with rosaceaen_US
dc.typeArticleen_US

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