ANTIFUNGAL ACTIVITY OF Nigella sativa L. AND Thymbra spicata L. ESSENTIAL OILS AGAINST Tricophyton rubrum

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dc.authoridKaya, Durmus Alpaslan/0000-0003-3544-9214
dc.contributor.authorKaya, Durmus Alpaslan
dc.contributor.authorDuran, Nizami
dc.date.accessioned2024-09-18T20:52:45Z
dc.date.available2024-09-18T20:52:45Z
dc.date.issued2018
dc.departmentHatay Mustafa Kemal Üniversitesien_US
dc.description7th International Conference on Advanced Materials and Systems -- OCT 18-20, 2018 -- Bucharest, ROMANIAen_US
dc.description.abstractIn this study, we aimed to investigate components and the antifungal activity of Nigella sativa L. and Thymbra spicata L. essential oils against Tricophyton rubrum. Thirty-nine essential oil components, representing 99,69 %, were detected in the essential oil of Thymbra spicata L. The major essential oil constituents were carvacrol (58,32 %), gamma-terpinene(28,53 %),o-cymene (5,20 %) and a-terpinene (2,03 %). Twenty-four essential oil components, representing 98,39 %, were detected in the essential oil of Nigella sativa L. The major essential oil constituents were anethole (22.97 %), thymoquinone (21.36 %), alpha-thujene (6.22 %), longifolene (5.76 %), trans-isoeugenol (3.55 %) and carvacrol (2.23 %). Antifungal activity of the essential oils of Nigella Sativa and Thymbra spicata was evaluated microdilution method. Fluconazole was selected as the standard antifungal drug. The activity of Nigella sativa L. and Thymbra spicata L. essential oils against T. rubrum was quite high. While Nigella sativa L. essential oils had MIC and MBC values of 1 and 2, Thymbra spicata L. essential oils were remarkable against T. rubrum. Thymbra spicata L. essential oils had the best MIC and MBC values (6.25 and 12.5 mg/ml). In our study, the efficacy of Thymbra spicata L. essential oils against Tricophyton rubrum was found higher. It seems that the essential oils of Nigella sativa L. and Thymbra spicata L. contain active components against rubrum, which is an important effect of superficial fungal infections.en_US
dc.description.sponsorshipMinist Res & Innovat,Natl Res & Dev Inst Textile & Leather, Div Leather & Footwear Res Insten_US
dc.identifier.doi10.24264/icams-2018.VIII.9
dc.identifier.endpage444en_US
dc.identifier.scopus2-s2.0-85100212643en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage439en_US
dc.identifier.urihttps://doi.org/10.24264/icams-2018.VIII.9
dc.identifier.urihttps://hdl.handle.net/20.500.12483/11368
dc.identifier.wosWOS:000464905000070en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherIncdtp-Icpien_US
dc.relation.ispartofProceedings of The 7th International Conference on Advanced Materials and Systemsen_US
dc.relation.publicationcategoryKonferans Öğesi - Uluslararası - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectNigella Sativa and Thymbra spicata essential oils against T. rubrum Candidaen_US
dc.subjectantifungalen_US
dc.titleANTIFUNGAL ACTIVITY OF Nigella sativa L. AND Thymbra spicata L. ESSENTIAL OILS AGAINST Tricophyton rubrumen_US
dc.typeConference Objecten_US

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