Polyglycolic acid copolymers from one-step cationic polymerization of formaldehyde, carbon monoxide, and epoxides derived from PEG
Yükleniyor...
Tarih
2019
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Wiley
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Biodegradable polyglycolic acid (PGA) is conventionally produced via the ring-opening polymerization of glycolide, the cyclic dimer form of glycolic acid, in the presence of mostly tin-based catalyst initiators which are rather known to be cytotoxic materials. Our previous studies revealed an alternative method for the synthesis of PGA from the perfectly alternating copolymerization of formaldehyde (from trioxane) and carbon monoxide (CO) under Bronsted acidic conditions. The poor physical properties of PGA (insolubility in many organic solvents, brown color, etc.) limit its use in other marketing applications in the industry. To improve on the physical properties of PGA, such as solubility and appearance, copolymerization of trioxane, CO, and a minor amount of epoxides derived from polyethylene glycol (PEG) were performed under the same reaction conditions for PGA synthesis (in DCM, at 800 psi CO pressure, with triflic acid catalyst, reaction duration of 72 hours). The results have shown that the addition of minor quantities of epoxide comonomers vastly improves the appearance of the obtained PGA copolymers and allows for the control of the polymeric properties, such as solubility and melting temperature.
Açıklama
Anahtar Kelimeler
carbon monoxide and epoxide, formaldehyde, polyglycolic acid (PGA), trioxane
Kaynak
Polymers For Advanced Technologies
WoS Q Değeri
Q2
Scopus Q Değeri
Q2
Cilt
30
Sayı
7
